| dc.description.abstract | Flavonoids and quercetin are metabolite compounds contained in parasite plants. The role
of the compounds is as an antioxidant that can protect cell damage from free radicals,for
example liver. Liver is an organ that is vulnerable to damage caused by drugs or toxic
chemicals because the liver is the center of metabolism in the body. Can be known with
indicators of increasing level of SGOT, SGPT total bilirubin and histopathologic liver. The
purpose of this study to determine the effect of the combination of extracts of tea parasite
and mango parasite (EMBTBM) on levels of liver function in female rats (Rattus
norvegicus) for 28 days. Data were analyzed using ANOVA version Jamovi 1.0.1.0.. The
number of test animals is 20 female rats were divided into four groups, group 1 as a
control, group 2,3,4 as a treatment. The treatment groups was given EMBTBM with
different doses of 250 mg/kgBW, 500 mg/kgBW and 1000 mg/kgBW. Based on the research
results show that a significant value difference between the group was p> 0,05. Therefore
EMBTBM given to female rats for 28 days with a dose of 250 mg/BW, 500 mg/kgBW and
1000 mg/kgBW in the treatment group all dose were not significantly different compared
with controls. So that the level of liver function as SGOT, SGPT, total bilirubin and
histopathology in female rats wasnot toxic and has no effect on liver histopathology of
female wistar rats.
Keyword: Subchronic, Extract and liver function | en_US |
