Browsing LP - Faculty of Medicine by Issue Date

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Anti-hiperglycemic Effect of Urena lobata Leaf Extract by Inhibition of Dipeptidyl Peptidase IV ( DPP-IV ) on Diabetic Rats

Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A (International Journal of Pharmacognosy and Phytochemical research (IJPPR), 2015-01-19)

Glucagon Like Peptide-1 (GLP-1) is one of incretin hormone which is proposed as a new therapy for type 2 diabetes (T2DM). However, this hormone is metabolized excessively by Dipeptidyl Peptidase IV (DPP-IV) into inactive ...
Anti-diabetic potential of Urena lobata leaf extract through inhibition of dipeptidyl peptidase IV activity

Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A (Asian Pacific Journal of Tropical Biomedicine, 2015-08-01)

Objective To evaluate the anti-diabetic potential of leaf extract from Urena lobata (U. lobata) through dipeptidyl peptidase IV (DPP-IV) inhibitory activity. Methods U. lobata leaf was extracted in hot water and ...
Factors related to rational antibiotic prescriptions in community health centers in Depok City, Indonesia

Andrajati, Retnosari; Tilaqza, Andri; Supardi, Sudibyo (Elsevier, 2016-01-12)

Irrational antibiotic prescription is common in developing countries, including in Indonesia. The aims of this study were to evaluate antibiotic prescription patterns and the factors related to the rationale for antibiotic ...
Design and Molecular Docking Studies of Quinazoline Derivatives as Antiproliferation

Widiyana, Anita P; Putra, Galih S; Muclashi, Luthfi A (Fakultas Farmasi Universitas Airlangga, 2016-12-02)

Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ...
Comparison of DNA Extraction Methods Between Conventional, Kit, Alkali and Buffer-Only for PCR Amplification on Raw and Boiled Bovine and Porcine Meat

Yahya, Arif; Firmansyah, Marindra; Arlisyah, Annisa; Risandiansyah, Rio (Universitas Brawijaya, 2017)

Detection of porcine contamination in food material by employing PCR techniques is integral in halal food confirmation. However, PCR is both costly and laborious, particularly in DNA isolation method. This study explores ...
Atheroprotective Effect of The Agaricus Blazei Mur ill Extract in High Fat Diet-Induced Mice

Kurniawan, Dicky; Djanggan, Sargowo; Askandar, Tjokroprawiro; Muhaimin, Rifa'i (Medicinal Plants, 2017-02-20)

The purpose of the present study was to provide evidence of the potential of Agaricus blazei Murill extract as atheroprotective agent. The study was conducted with 25 male mice (Mus musculus) divided into f ive groups ...
Study of Superoxide Dismutase and Malondialdehyde Concentrations in Mice After Administration of Methanolic Extract of Scurrula Atropurpurea (BL.)

Athiro, Nour; Wahyuningsih, Doti (Fakultas Kedokteran Hewan, Universitas Syiah Kuala, 2017-03)

The aim of this research was to investigate the potential effect of methanolic extract of Scurrula atropurpurea (MESA) in reducing oxidative stress through observation of superoxide dismutase (SOD) activity and malondialdehyde ...
Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo

Wahyuningrum, Ike; Hariyadi, D. M; Hendradi, E (MRI Publications Lucknow, Uttar Pradesh, India, 2017-04-20)

Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC ...
Combined Effects of Shear Stress and Glucose on the Morphology, Actin Filaments, and VE-Cadherin of Endothelial Cells in Vitro

Sulistyowati, Erna; Permatasari, Nur; Widodo, M Aris (Elsevier, 2017-06-07)

Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin. Methods: After ...
Revealing The Potency of Annona Muricata Leaves Extract as FOXO1 Inhibitor for Diabetes Mellitus Treatment Through Computational Study

Damayanti, Dini Sri; Utomo, Didik Huswo; Kusuma, Chandra (Springer, 2017-06-26)

FOXO1 protein inactivation in the nucleus is one of targets for the treatment of diabetes mellitus. Annona muricata leaves contain flavonoid and phenolic compound alkaloids that were known to be able to increase pancreatic ...
Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells

Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A (Elsevier, 2017-07-20)

This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test ...
Synthesis, Method Optimization of 2,3-Disubtitutedquinazolin-4(3H)-One

Widiyana, Anita P; Putra, Galih S; Sulistyowati, Mellany Ika; Hardjono, Suko; Budiati, Tutuk (Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)

Quinzolinones have various biological activities such as anticancer, antidiabetic, anticonvulsant, antihistaminic, anti inflammatory, antifungal, anthelmintics and antiviral activites. In this research some of compounds ...
The Influence of Ratio Pyridine and Triethylamine Catalysts on Synthesis 2-Phenyl-Benzo[D] [1,3] Oxazine-4-On Derivatives

Putra, Galih S; Widiyana, Anita P; Muchlashi, Luthfi A; Sulistyowati, Mellany I; Ekowati, Juni; Budiati, Tutuk (Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)

The aim of this research was to compare the effect of pyridine and triethylamine catalyst ratios on the synthesis of 2-phenyl-benzo(d)[1,3] oxazine-4-one derivatives. The catalysts used were triethylene amine (100%), ...
Indonesian Herbal Medicine Prevents Hypertension-Induced Left Ventricular Hypertrophy by Diminishing NADPH Oxidase-Dependent Oxidative Stress

Sulistyowati, Erna; Hsu, Jong-Hau; Cheng, Yuan-Bin; Chang, Fang-Rong; Cheng, Ying-Fu; Yeh, Jwu-Lai (US National Library of Medicine National Institutes of Health, 2017-09-30)

Indonesian herbal medicine Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension. Oxidative stress plays an important role in hypertension-induced ...
Evaluasi Hasil Penerapan Model Sms Gateway dalam Promosi Kesehatan Tentang Bahaya Komplikasi Selama Kehamilan

Herlina, Sri (Universitas Almaata & Universitas Islam Indonesia, 2018)

Penerapan teknologi berbasis sms gateway penting dikembangkan sebagai alternatif strategi pendekatan pada komunitas yang sulit terjangkau fasilitas kesehatan dalam rangka menurunkan angka kematian baik pra maternal maupun ...
Metode Slow Sand Filter dan Pengukuran MPN Coliform Sebagai Upaya Peningkatan Kualitas Air Sungai di Pekapuran Raya Banjarmasin

Herlina, Sri (Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018)

Sungai Pekapuran Raya Banjarmasin merupakan salah satu kawasan pinggiran sungai yang padat penduduk, saat musim kemarau kondisi sungai terlihat dangkal dipenuhi tumpukan sampah, berwarna kecoklatan dan keruh. Penelitian ...
Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation

Yang, Dongqing; Anderson, Paul H.; Wijeyanaka, Asiri R.; Barratt, Kate R.; Triliana, Rahma; Stapledon, Catherine J.M.; Zhou, Hong; Findlay, David M.; Morris, Howard A.; Atkins, Gerald J. (Elsevier, 2018)

Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ...
Cardiovascular protective effect of Indonesian herbal medicine in spontaneously hypertensive rats

Yeh, Jwu-Lai; Sulistyowati, Erna (J-STAGE, 2018)
Antidiabetic Effect of Urena lobata: Preliminary Study on Hexane, Ethanolic, and Aqueous Leaf Extracts

Wahyuningsih, Doti; Purnomo, Yudi (Jurnal Universitas Brawijaya, 2018-02-20)

Chronic hyperglycemia is one of the signs of human type-2 diabetes mellitus due to insulin resistance and depletion. This study aimed to evaluate hexane, ethanolic, and aqueous leaf extracts of Urena lobata as antihyperglycemic ...
Terapi dengan Dinydroartemisinin Piperaquine (DHP) dapat Mencegah Terjadinya Anemia Tetapi Tidak Dapat Mencegah IUGR pada Mencit Bunting yang di Infeksi Plasmodium berghei

Andriana, Diah (Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018-03-20)

Infeksi malaria dengan Plasmodium falciparum selama kehamilan berhubungan dengan infeksi pada plasenta dan dampak buruk yang luas pada ibu maupun janin yang dikandungnya meliputi salah satunya anemia pada ibu hamil ...

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