Browsing LP - Medical Education by Title
Now showing items 9-28 of 34
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The Effect of Darapladib Therapy for the Expression of Lp-PLA2 in Dyslipidemia and Type 2 Diabetes Mellitus Atherosclerosis Model
(Journal of Applied Pharmaceutical Science, 2018-04-29)Atherosclerosis is the main cause of mortality and morbidity globally. Lipoprotein-associated phospholipase A2 (LpPLA2 ) activity is suspected to have a significant role in atherosclerosis. 50 Sprague-Dawley Rats were ... -
Effects of Soursop (Annona muricata ) Leaf Water Extract (SLWE) on Body Weight, Leptin and TNF α Plasma Levels of Rats with High Fat and High Fructose (HFHF) Diet.
(Journal of Global Pharma Technology, 2019-04)Background: Soursop leaves believed to be able to lose weight. The aim of the study was to prove that SLWE had an effect on body weight, leptin and TNF α plasma level in mice with the HFHF diet . Methods:The study used ... -
Evaluasi Hasil Penerapan Model Sms Gateway dalam Promosi Kesehatan Tentang Bahaya Komplikasi Selama Kehamilan
(Universitas Almaata & Universitas Islam Indonesia, 2018)Penerapan teknologi berbasis sms gateway penting dikembangkan sebagai alternatif strategi pendekatan pada komunitas yang sulit terjangkau fasilitas kesehatan dalam rangka menurunkan angka kematian baik pra maternal maupun ... -
Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages
(MDPI journals, 2018-08-23)Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic ... -
HUBUNGAN KUANTITATIF STRUKTUR-PROPERTI (HKSP) SENYAWA AKTIF TEMU KUNCI (BOESENBERGIA PANDURATA) SEBAGAI PENGHAMBAT ENZIM MAIN PROTEASE (MPRO) SARS-CoV-2
(Sanata Dharma University Press, 2022-12-10)Hubungan parameter fisikokimia dari 15 senyawa aktif Boesenbergia pandurata dalam menghambat enzim main protease SARS-CoV-2 diprediksi melalui model Hubungan Kuantitatif Struktur-Properti (HKSP). Semua senyawa aktif ... -
In Silico Study to Assess Antibacterial Activity from Cladophora Sp. on Peptide Deformylase: Molecular Docking Approach
(Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya, 2019-05-04)Increasing antibiotic-resistant pathogenic bacteria is a severe problem in the world. Therefore, there is a need to identify new drugs from natural products and also new drug targets. Cladophora sp. is a marine organism ... -
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
(National Library of Medicine, 2021-05-28)Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ... -
Indonesian Herbal Medicine Prevents Hypertension-Induced Left Ventricular Hypertrophy by Diminishing NADPH Oxidase-Dependent Oxidative Stress
(US National Library of Medicine National Institutes of Health, 2017-09-30)Indonesian herbal medicine Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension. Oxidative stress plays an important role in hypertension-induced ... -
Indonesian Pasuruan Propolis Extract Does Not Exert Antiproliferation and Pro-Apoptotic Effect on Human Colon Carcinoma Cell Line HT-29
(AFRICAN JOURNALS ONLINE (AJOL), 2018-07-20)Purpose: To evaluate the anti-cancer activity of Indonesian Pasuruan propolis extract (PPE) against HT-29 human colon carcinoma cell line. Methods: HT-29 cells were cultured and treated in different concentrations of PPE ... -
Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene
(Springer, 2018-09-06)Extracellular superoxide dismutase (EC-SOD) has been implicated in regulation of vascular function but its underlying molecular mechanism is largely unknown. These two-step experiments investigate whether hemagglutinating ... -
The Interaction of β-Glucan on Dectin-1 Receptor or TLR-2 Might Have the Potency to Activate Function of Treg Cell and Production of Anti-Inflammatory Cytokine
(EurAsian Journal of BioSciences, 2020-03-20)Objectives: Atherosclerosis formed due to the accumulation of the fibrous tissues in the vascular wall and gradually become thrombus. Agaricus brasiliensis known as a traditional drug for lifestylerelated diseases, including ... -
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways
(MDPI journals, 2019-04-08)To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ... -
Korelasi IgE Terhadap Rasio Neutrofil/Eosinofil Jaringan dan Darah Penderita Rinosinusitis Kronik Aspergillus Fumigatus
(Oto Rhino Laryngologica Indonesiana, 2018-06-01)Latar Belakang: Prevalensi rinosinusitis kronik (RSK) jamur saat ini cenderung meningkat. Jamur berperan sebagai mikroorganisme dan merupakan salah satu penyebab RSK. Pemeriksaan immunoglobulin E (IgE) Aspergillus ... -
Lp-PLA2 Selective Inhibitor (Darapladib) Effect In Lowering The Expression Level Of IL-1B And IL-6 In The Renal At Type 2 Diabetes Mellitus
(US National Library of Medicine National Institutes of Health, 2019-11-01)Purpose The aim of this study is to prove that type 2 diabetes mellitus can induce increasing inflammation marker in renal and that the provision of darapladib as Lp-LA2 Inhibitor agents can inhibit inflammation that were ... -
Metode Slow Sand Filter dan Pengukuran MPN Coliform Sebagai Upaya Peningkatan Kualitas Air Sungai di Pekapuran Raya Banjarmasin
(Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018)Sungai Pekapuran Raya Banjarmasin merupakan salah satu kawasan pinggiran sungai yang padat penduduk, saat musim kemarau kondisi sungai terlihat dangkal dipenuhi tumpukan sampah, berwarna kecoklatan dan keruh. Penelitian ... -
Perbedaan Ekspresi Protein Cyclin D1 antara Adenoma dan Adenokarsinoma Kolorektal, serta Korelasinya dengan Grading dan Stadium Tumor
(Fakultas Kedokteran Universitas Brawijaya, 2020-03-20)Sebagian besar karsinoma kolorektal adalah adenokarsinoma, dan lebih dari 95% karsinoma kolorektal diawali oleh lesi prekursor yaitu adenoma. Risiko suatu adenoma berubah menjadi suatu karsinoma akan lebih tinggi pada ... -
The Potency of Soursop Leaf Water Extract on Activating GLP-1R, Inhibiting DPP4 And FoxO1 Protein Based on in Silico Analysis
(International Journal of Applied Pharmaceutics, 2019-12-15)Objective: Soursop leaf contains alkaloids, terpenoids, flavonoids, acetogenin, and phenolics. Soursop leaf decoction is usually consumed as an anti obesity agent, even though its active compounds and its action mechanism ... -
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine
(MDPI journals, 2020-10-06)Vascular calcification (VC) is highly prevalent in patients with atherosclerosis, chronic kidney disease, diabetes mellitus, and hypertension. In blood vessels, VC is associated with major adverse cardiovascular events. ... -
Profile of Patients with Floaters in Saiful Anwar Hospital Malang
(Indonesian Vitreoretinal Society, 2018-08-24)Introduction: To report the profile of patients with floaters as a subjective complain in Saiful Anwar Hospital from July 2012 until June 2013. Methods: an observasional descriptive study was conducted, collecting data ... -
The Prophylactic Effects of Pomegranate Peel in a Rat Model of Rheumatoid Arthritis: Study on Arthritis Score and Expression of Inflammatory Markers
(Jurnal Universitas Brawijaya, 2020)Rheumatoid arthritis (RA) is a joint disease, chronically cause permanent joint impairment leading to inability of daily life activities. Early diagnosis and preven tive managements of RA are recommended to overcome the ...