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Browsing LP - Medical Education by Issue Date

Browsing LP - Medical Education by Issue Date

Now showing items 21-34 of 34

Effects of Soursop (Annona muricata ) Leaf Water Extract (SLWE) on Body Weight, Leptin and TNF α Plasma Levels of Rats with High Fat and High Fructose (HFHF) Diet.

Damayanti, Dini Sri; Kusuma, Chandra; Nurdiana; Soeadmadji, Djoko Wahono (Journal of Global Pharma Technology, 2019-04)

Background: Soursop leaves believed to be able to lose weight. The aim of the study was to prove that SLWE had an effect on body weight, leptin and TNF α plasma level in mice with the HFHF diet . Methods:The study used ...
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

Lee, Meng-Luen; Sulistyowati, Erna; Hsu, Jong-Hau; Huang, Bo-Yau; Dai, Zen-Kong; Wu, Bin-Nan; Chao, Yu-Ying; Yeh, Jwu-Lai (MDPI journals, 2019-04-08)

To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ...
In Silico Study to Assess Antibacterial Activity from Cladophora Sp. on Peptide Deformylase: Molecular Docking Approach

Bintari, Yoni Rina; Risandiansyah, Rio (Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya, 2019-05-04)

Increasing antibiotic-resistant pathogenic bacteria is a severe problem in the world. Therefore, there is a need to identify new drugs from natural products and also new drug targets. Cladophora sp. is a marine organism ...
Vasculoprotective Effects of Centella Asiatica, Justicia Gendarussa and Imperata Cylindrica Decoction via the NOXs-ROS-NF-κB Pathway in Spontaneously Hypertensive Rats

Sulistyowati, Erna; Jan, Ren-Long; Liou, Shu-Fen; Chen, Ying-Fu; Wu, Bin-Nan; Hsu, Jong-Hau; Yeh, Jwu-Lai (Elsevier, 2019-06-24)

Background and aim: Centella asiatica,Justicia gendarussaandImperata cylindricadecoction (CJID) isefficacious for hypertension. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-induced reactive oxygen ...
Dietary Ethanolic Extract of Mangosteen pericarp Reduces VCAM-1, Perivascular Adipose Tissue and Aortic Intimal Medial Thickness in Hypercholesterolemic Rat Model

Wihastuti, Titin Andri; Aini, Fitria Nugraha; Tjahjono, Cholid Tri; Heriansyah, Teuku (US National Library of Medicine National Institutes of Health, 2019-10-10)

BACKGROUND: High-fat diet (HFD) is associated with dyslipidemia which is a risk factor for atherosclerosis. Dyslipidemia causes oxidative stress which induces vascular cell adhesion molecule-1 (VCAM-1). Oxidative stress ...
Lp-PLA2 Selective Inhibitor (Darapladib) Effect In Lowering The Expression Level Of IL-1B And IL-6 In The Renal At Type 2 Diabetes Mellitus

Wihastuti, Titin Andri; Aini, Fitria Nugraha; Tjahjono, Cholid Tri; Sulfia, Yuni Hendrati; Sholichah, Zuhrotus; Heriansyah, Teuku (US National Library of Medicine National Institutes of Health, 2019-11-01)

Purpose The aim of this study is to prove that type 2 diabetes mellitus can induce increasing inflammation marker in renal and that the provision of darapladib as Lp-LA2 Inhibitor agents can inhibit inflammation that were ...
The Potency of Soursop Leaf Water Extract on Activating GLP-1R, Inhibiting DPP4 And FoxO1 Protein Based on in Silico Analysis

Damayanti, Dini Sri; Nurdiana; Kusuma, Chandra; Soeadmadji, Djoko Wahono (International Journal of Applied Pharmaceutics, 2019-12-15)

Objective: Soursop leaf contains alkaloids, terpenoids, flavonoids, acetogenin, and phenolics. Soursop leaf decoction is usually consumed as an anti obesity agent, even though its active compounds and its action mechanism ...
The Prophylactic Effects of Pomegranate Peel in a Rat Model of Rheumatoid Arthritis: Study on Arthritis Score and Expression of Inflammatory Markers

Wahyuningsih, Doti; Amalia, Annisa; Amiruddin, Meilano Setiawan; Cahyaningrum, Asri; Kurniasari, Laili Chintianur (Jurnal Universitas Brawijaya, 2020)

Rheumatoid arthritis (RA) is a joint disease, chronically cause permanent joint impairment leading to inability of daily life activities. Early diagnosis and preven tive managements of RA are recommended to overcome the ...
Perbedaan Ekspresi Protein Cyclin D1 antara Adenoma dan Adenokarsinoma Kolorektal, serta Korelasinya dengan Grading dan Stadium Tumor

Rosidah, Aris; Norahmawati, Eviana; Anita, Kenty Wanty; Rasyid, Harun Al (Fakultas Kedokteran Universitas Brawijaya, 2020-03-20)

Sebagian besar karsinoma kolorektal adalah adenokarsinoma, dan lebih dari 95% karsinoma kolorektal diawali oleh lesi prekursor yaitu adenoma. Risiko suatu adenoma berubah menjadi suatu karsinoma akan lebih tinggi pada ...
The Interaction of β-Glucan on Dectin-1 Receptor or TLR-2 Might Have the Potency to Activate Function of Treg Cell and Production of Anti-Inflammatory Cytokine

Kurniawan, Dicky; Sargowo, Djanggan; Tjokroprawiro, Askandar; Rifa'i, Muhaimin (EurAsian Journal of BioSciences, 2020-03-20)

Objectives: Atherosclerosis formed due to the accumulation of the fibrous tissues in the vascular wall and gradually become thrombus. Agaricus brasiliensis known as a traditional drug for lifestylerelated diseases, including ...
The Significance of Agaricus Blazei as an Immunomodulator of The Level of IL-17 in Balb/C mice with Atherosclerosis

Kurniawan, Dicky; Djanggan, Sargowo; Tjokroprawiro, Askandar (National Center for Biotechnology Information, U.S. National Library of Medicine, 2020-04-20)

Atherosclerosis is a disease caused by an inflammatory response which involved the interaction between endothelial cells, macrophages and lymphocytes, and is closely related to IL-17 regulation. This study is important to ...
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine

Liou, Shu-Fen; Nguyen, Thi Tuyet Ngan; Hsu, Jong-Hau; Sulistyowati, Erna; Huang, Shang-En; Wu, Bin-Nan; Lin, Ming-Chung; Yeh, Jwu-Lai (MDPI journals, 2020-10-06)

Vascular calcification (VC) is highly prevalent in patients with atherosclerosis, chronic kidney disease, diabetes mellitus, and hypertension. In blood vessels, VC is associated with major adverse cardiovascular events. ...
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis

Huang, Shang-En; Sulistyowati, Erna; Chao, Yu-Ying; Wu, Bin-Nan; Dai, Zen-Kong; Hsu, Jong-Hau; Yeh, Jwu-Lai (National Library of Medicine, 2021-05-28)

Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ...
HUBUNGAN KUANTITATIF STRUKTUR-PROPERTI (HKSP) SENYAWA AKTIF TEMU KUNCI (BOESENBERGIA PANDURATA) SEBAGAI PENGHAMBAT ENZIM MAIN PROTEASE (MPRO) SARS-CoV-2

Widiyana, Anita Puspa (Sanata Dharma University Press, 2022-12-10)

Hubungan parameter fisikokimia dari 15 senyawa aktif Boesenbergia pandurata dalam menghambat enzim main protease SARS-CoV-2 diprediksi melalui model Hubungan Kuantitatif Struktur-Properti (HKSP). Semua senyawa aktif ...

Browsing LP - Medical Education by Issue Date

Browsing LP - Medical Education by Issue Date

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