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Browsing LP - Medical Education by Author "Wu, Bin-Nan"

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Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

Sulistyowati, Erna; Lee, Mei-Yueh; Wu, Lin-Chi; Hsu, Jong-Hau; Dai, Zen-Kong; Wu, Bin-Nan; Lin, Ming-Chung; Yeh, Jwu-Lai (MDPI journals, 2018-08-23)

Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic ...
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis

Huang, Shang-En; Sulistyowati, Erna; Chao, Yu-Ying; Wu, Bin-Nan; Dai, Zen-Kong; Hsu, Jong-Hau; Yeh, Jwu-Lai (National Library of Medicine, 2021-05-28)

Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ...
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

Lee, Meng-Luen; Sulistyowati, Erna; Hsu, Jong-Hau; Huang, Bo-Yau; Dai, Zen-Kong; Wu, Bin-Nan; Chao, Yu-Ying; Yeh, Jwu-Lai (MDPI journals, 2019-04-08)

To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ...
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine

Liou, Shu-Fen; Nguyen, Thi Tuyet Ngan; Hsu, Jong-Hau; Sulistyowati, Erna; Huang, Shang-En; Wu, Bin-Nan; Lin, Ming-Chung; Yeh, Jwu-Lai (MDPI journals, 2020-10-06)

Vascular calcification (VC) is highly prevalent in patients with atherosclerosis, chronic kidney disease, diabetes mellitus, and hypertension. In blood vessels, VC is associated with major adverse cardiovascular events. ...
Vasculoprotective Effects of Centella Asiatica, Justicia Gendarussa and Imperata Cylindrica Decoction via the NOXs-ROS-NF-κB Pathway in Spontaneously Hypertensive Rats

Sulistyowati, Erna; Jan, Ren-Long; Liou, Shu-Fen; Chen, Ying-Fu; Wu, Bin-Nan; Hsu, Jong-Hau; Yeh, Jwu-Lai (Elsevier, 2019-06-24)

Background and aim: Centella asiatica,Justicia gendarussaandImperata cylindricadecoction (CJID) isefficacious for hypertension. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-induced reactive oxygen ...

Browsing LP - Medical Education by Author "Wu, Bin-Nan"

Browsing LP - Medical Education by Author "Wu, Bin-Nan"

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