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Title: | Histopathological Profile of Therapeutic Doses of Mango Mistletoe Methanolic Extract (MMME) in Cardiac of Hypertensive Rats (DOCA-Salt) |
Authors: | Hakimah, Annisatul Sjakoer, Nour Mubarakati, Nurul |
Keywords: | Hypertension Methanolic Extract Mango Benalu Cardiac Histopathology DOCA-salt |
Issue Date: | Apr-2021 |
Publisher: | JSMARTech: Journal of Smart Bioprospecting and Technology |
Series/Report no.: | Vol 2, No 2; |
Abstract: | This study determined the effect of Mango mistletoe Methanolic Extract (MMME) on the cardiac's histopathological profile of hypertensive rats (DOCA-Salt) treated. The MMME was treated on fifty rats for 14 days, divided into five treatments: negative control, positive control, doses 50, 100, and 200 mg/kg BW with five replications. One-way ANOVA analysis was used, namely JAMOVI with version 1.1.9.0, and for cell calculation, diameter using the IMAGE J application. Results showed that there were no significant differences in the histopathological profile of the cardiac in hypertensive rats (DOCA-Salt) treated with MMME for 14 days on the diameter of the heart muscle cells between the control (+) and control groups (-), treatments 1, 2, and 3. This is evidenced by the analysis of p-value> 0.05, namely 0.187 millimeters. Therefore, we concluded that MMME does not affect the diameter of heart/cardiac organ muscle cells. However, there was a significant difference in the amount of necrosis in the cardiac of hypertensive rats between control (+) and control (-) groups, treatments 1, 2, and 3. Based on the results, MMME reduces the number of necrosis in the heart/cardiac organ. |
Description: | [ARCHIVES] Copyright Article from : JSMARTech: Journal of Smart Bioprospecting and Technology, https://jsmartech.ub.ac.id/index.php/jsmartech/article/view/34 |
URI: | https://jsmartech.ub.ac.id/index.php/jsmartech/article/view/34 http://repository.unisma.ac.id/handle/123456789/2062 |
ISSN: | 2714-7894 |
Appears in Collections: | LP - Biology |
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1. CHECK PLAGIARISME_JSMARTECH_Histopathological Profile of Therapeutic Doses of Mango Mistletoe Methanolic Extract (MMME) in Cardiac of Hypertensive Rats (DOCA-Salt).pdf | 3.13 MB | Adobe PDF | View/Open | |
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