Hydroponics is agricultural cultivation without using soil media, where the media can be replaced with husk charcoal or cocopeat media. However, hydroponics is actually the use of nutrients in a solution so that the nutritional needs of the plant are as desired. Accordingly, plant growth can be maximized. The use of media other than soil does not inhibit plant growth because both charcoal husk and cocopeat can store nutrients so that plant growth is not disturbed. This study aims to determine the response of red spinach (Alternanthera amoena Voss.) to Cocopeat and husk charcoal, and also to determine the use of DFT (Deep Flow Technique) and NFT (Nutrient Film Technique) hydroponic systems on the growth and development of red spinach. The method used was RBD where Rockwool media as a control, with 6 treatments and 4 replications. From the research results, the cocopeat media and husk charcoal media gave different results where the cocopeat growing medium was greater than the husk charcoal growing medium and the DFT and NFT systems gave significantly different results where the NFT yield was greater than DFT. Keywords: Hydroponics, Red Spinach, Cocopeat, Husk Charcoal, DFT, NFT