Computer-Mediated Communicationis one of the technologies that can be used to communicate through video calls, messages, send pictures, etc to the people we want to communicate with throughout the world. The purpose of this research is to complete the previous study by conducting research students of the University.There are two kinds of CMC as follows: Synchronous CMC and Asynchronous CMC. Those can be used often by the people for their study especially for communication by speaking (English) and by writing. This study used a descriptive qualitative method. The researcher used a questionnaire and interview as the instrument. The participants were 40 students as the sample of questionnaires and 5 students of interview. The researcher shared a digital questionnaire (Google Form) and interview by chat on Whatsapp to collect the data. Since the research objectives are to find out and to describe the students of academic year 2021/2022 about students’ perception on the use of CMC for speaking skill. The first step was to find the percentage in the percent diagram by using automatic result from the questionnaire data on Google Form, and the second step was interview documentation by chat messages on Whatsapp. Almost all the students agree that CMC has a positive influence on the development of student’s speaking. And can be used as a continuation in learning other skill in English. That can be seen between synchronous and asynchronous almost the all students use synchronous in communication and they had an access to connect to the internet every day. The researcher concluded that: almost all question and statements show a positive perceptions and the implementation of CMC which have an impact on improving student’s ability to communicate and interact using English in their daily lives. However, one of the result also showed a neutral student’s perception of not experiencing difficulties when communication directly. Suggestions for the Students and teachers are advised to frequently use CMC in learning, especially when outside the classroom and for the other reserachers are advised to conduct research using more in-depth research problems related to CMC and try to find more strategies research settings. Keyword: Computer-Mediated Communication, Perception, Speaking Skill