Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo

Wahyuningrum, Ike; Hariyadi, D. M; Hendradi, E

dc.contributor.author	Wahyuningrum, Ike
dc.contributor.author	Hariyadi, D. M
dc.contributor.author	Hendradi, E
dc.date.accessioned	2022-02-23T05:09:48Z
dc.date.available	2022-02-23T05:09:48Z
dc.date.issued	2017-04-20
dc.identifier.issn	0975-4415
dc.identifier.uri	https://www.myresearchjournals.com/index.php/IJDDT/article/view/10657
dc.identifier.uri	http://repository.unisma.ac.id/handle/123456789/3109
dc.description	[ARCHIVES] Copyright Article from: INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY (MRI Publications Lucknow, Uttar Pradesh, India)	en_US
dc.description.abstract	Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC meloxicam was repared using emulsification methodwith three different lipid ratio. . NLC meloxicam was prepared and characterized for measuring the pH, viscocity, particle size, and entrapment efficiency. The rat paw edema test was performed to evaluate the antiinflammatory activity of three formulations NLC meoxicam. Results : based on research result shows that the smaller the solid lipid concentrations, particle size is the larger, the greater viscosity, thus increasing occlusive NLC to the skin. The third formula hasthe greatest solid lipid concentration shows the smallest AUC value but once in a statistical test known to be significantly different from the three formulas. Conclusions : NLC meloxicam showed that it had anti-inflammatory effectiveness	en_US
dc.language.iso	en	en_US
dc.publisher	MRI Publications Lucknow, Uttar Pradesh, India	en_US
dc.relation.ispartofseries	INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY;Vol.7, Issue 4
dc.subject	NLC	en_US
dc.subject	meloxicam	en_US
dc.subject	antiinflammatory	en_US
dc.subject	paw edema	en_US
dc.title	Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo	en_US
dc.type	Article	en_US