Browsing LP - Pharmaceutical by Issue Date
Now showing items 1-20 of 27
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Anti-hiperglycemic Effect of Urena lobata Leaf Extract by Inhibition of Dipeptidyl Peptidase IV ( DPP-IV ) on Diabetic Rats
(International Journal of Pharmacognosy and Phytochemical research (IJPPR), 2015-01-19)Glucagon Like Peptide-1 (GLP-1) is one of incretin hormone which is proposed as a new therapy for type 2 diabetes (T2DM). However, this hormone is metabolized excessively by Dipeptidyl Peptidase IV (DPP-IV) into inactive ... -
Anti-diabetic potential of Urena lobata leaf extract through inhibition of dipeptidyl peptidase IV activity
(Asian Pacific Journal of Tropical Biomedicine, 2015-08-01)Objective To evaluate the anti-diabetic potential of leaf extract from Urena lobata (U. lobata) through dipeptidyl peptidase IV (DPP-IV) inhibitory activity. Methods U. lobata leaf was extracted in hot water and ... -
Factors related to rational antibiotic prescriptions in community health centers in Depok City, Indonesia
(Elsevier, 2016-01-12)Irrational antibiotic prescription is common in developing countries, including in Indonesia. The aims of this study were to evaluate antibiotic prescription patterns and the factors related to the rationale for antibiotic ... -
Design and Molecular Docking Studies of Quinazoline Derivatives as Antiproliferation
(Fakultas Farmasi Universitas Airlangga, 2016-12-02)Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ... -
Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo
(MRI Publications Lucknow, Uttar Pradesh, India, 2017-04-20)Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC ... -
Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells
(Elsevier, 2017-07-20)This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test ... -
Synthesis, Method Optimization of 2,3-Disubtitutedquinazolin-4(3H)-One
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)Quinzolinones have various biological activities such as anticancer, antidiabetic, anticonvulsant, antihistaminic, anti inflammatory, antifungal, anthelmintics and antiviral activites. In this research some of compounds ... -
The Influence of Ratio Pyridine and Triethylamine Catalysts on Synthesis 2-Phenyl-Benzo[D] [1,3] Oxazine-4-On Derivatives
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)The aim of this research was to compare the effect of pyridine and triethylamine catalyst ratios on the synthesis of 2-phenyl-benzo(d)[1,3] oxazine-4-one derivatives. The catalysts used were triethylene amine (100%), ... -
Antidiabetic Effect of Urena lobata: Preliminary Study on Hexane, Ethanolic, and Aqueous Leaf Extracts
(Jurnal Universitas Brawijaya, 2018-02-20)Chronic hyperglycemia is one of the signs of human type-2 diabetes mellitus due to insulin resistance and depletion. This study aimed to evaluate hexane, ethanolic, and aqueous leaf extracts of Urena lobata as antihyperglycemic ... -
The difference of map1lc3 level as macrophage autophagy Marker between resistant and sensitive tuberculosis patients on rifampicin
(Lembaga Penyakit Tropis (Institute of Tropical Disease) Universitas Airlangga, 2018-04-01)M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be ... -
Inhibitory activity of Urena lobata leaf extract on dipeptidyl peptidase-4 (DPP-4):
(Society For Conservation And Resource Development Of Medicinal Plants, 2018-05-25)This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ... -
Inhibitory activity of Urena lobata leaf extract on dipeptidyl peptidase-4 (DPP-4): Is it different in vitro and in vivo?
(Medicinal Plants - International Journal of Phytomedicines and Related Industries, 2018-05-28)This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ... -
Acute Toxicity Level of Pulutan (Urena lobata) Leaf Extract on Zebrafish (Danio rerio) and its Analysis by In Silico Study
(The Japanese Pharmacological Society, The Japanese Society of Clinical Pharmacology, 2018-07-06)Pulutan (Urena lobata) is medicinal plant used to treat some diseases empirically, with pre-clinical study has already proven its efficacy, however, its safety has not been evaluated. Acute toxicity has to be performed on ... -
Potensi Toleransi Oral Glukosa Ekstrak Biji Kedelai (Glycine Max), Rimpang Jahe (Zingiber Officinale) Dan Kombinasinya Pada Tikus Model Diabetes
(Jurnal Kesehatan Islam (JKI), 2018-09-20)Diabetes Mellitus (DM) adalah sindrom metabolik yang ditandai peningkatan kadar glukosa darah kronik dan berkontribusi terhadap beberapa resiko komplikasi. Biji Kedelai(G.max) danrimpang Jahe (Z.officinale) digunakan sebagai ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP PERSENTASE INTERLEUKIN-10 (IL-10) DAN SEL T SITOTOKSIK (CD8+ ) TIKUS MODEL DIABETES Tipe II
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2019-03-01)Inflamasi akibat kerusakan oksidatif yang dipicu hiperglikemia berperan terhadap progresivitas diabetes melitus (DM). Interleukin-10 (IL-10) dan CD8+ berpengaruh terhadap proses inflamasi. Abelmoschus manihot (L.) Medik ... -
Effect of ascorbic acid, α-tocopherol and its combination on human umbilical vein endothelial cells permeability exposed to high concentration of glucose
(Russian Open Medical Journal, 2019-05-28)Aim — To evaluate the effect of ascorbic acid, α-tocopherol, and its combination on the permeability of human umbilical vein endothelial cells (HUVEC’S) culture after high glucose concentration exposure. Material and ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP KADAR SOD DAN MDA PADA AORTA TIKUS MODEL DIABETES MELITUS TIPE 2
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-03-01)Hiperglikemia pada diabetes melitus (DM) meningkatkan produksi reactive oxygen species (ROS) yang berperan terhadap komplikasi makroangiopati diabetik. Daun gedi merah dikenal memiliki efek antioksidan dan antihiperglikemia ... -
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER SHEET (SHEET MASK) KOMBINASI VCO (VIRGIN COCONUT OIL), ASAM ASKORBAT DAN α-TOCOPHEROL
(Fakultas Farmasi, Universitas Buana Perjuangan Karawang, 2020-05-09)Kulit yang sehat dapat mencerminkan kesehatan seseorang. Menjadikan kulit sehat, bersih dan cerah merupakan idaman semua orang terutama pada wanita. Antioksidan melindungi tubuh dari kerusakan yang disebabkan oleh radikal ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (ABELMOSCHUS MANIHOT (L.) MEDIK) TERHADAP KADAR SUPEROXIDE DISMUTASE DAN MALONDIALDEHYDE JARINGAN GINJAL TIKUS MODEL DIABETES MELITUS TIPE 2
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-09-12)Hiperglikemia pada Diabetes Melitus (DM) meningkatkan produksi Reactive Oxygen Species (ROS) dan berperan terhadap risiko komplikasi nefropati diabetik. Daun gedi merah (Abelmoschus manihot (L.) Medik) berkhasiat sebagai ... -
Effect of Extraction Method on Antimicrobial Activity Against Staphylococcus Aureus of Tapak Liman (Elephantopus Scaber L.) Leaves
(International journal of Health & Medical Sciences, 2020-10-18)This study aims to compare the antibacterial activity of Staphylococcus aureus from tapak liman leaf extract using different extraction methods, maceration, and soxhletation. Maceration is a type of cold extraction, ...