Wahyuningsih, Doti; Purnomo, Yudi; Tilaqza, Andri(Journal of Tropical Pharmacy and Chemistry (JTPC), 2022-06-30)
Inflammation is the basic for the pathogenesis of several diseases both of degenerative and non-degenerative disease. Urena lobata is a medicinal plant that can be found in Indonesia and has been used traditionally to cure ...
Purnomo, Yudi; Rejeki, Wara(Journal of Pharmaceutical Care Anwar Medika (JPhAM), 2022-07-04)
Peresepan obat yang tidak rasional merupakan masalah serius dalam pelayanan kesehatandi Indonesia. Faktor yang berperan terhadap kondisi ini adalah ketidaklengkapan dan ketidaksesuaian peresepan ...
Purnomo, Yudi(Jurnal Kesehatan Islam (JKI), 2020-09-20)
Diabetes Mellitus (DM) adalah sindrom metabolik yang ditandai peningkatan kadar glukosa darah kronik dan berkontribusi terhadap beberapa resiko komplikasi. Biji Kedelai(G.max) danrimpang Jahe (Z.officinale) digunakan sebagai ...
Objective
To evaluate the anti-diabetic potential of leaf extract from Urena lobata (U. lobata) through dipeptidyl peptidase IV (DPP-IV) inhibitory activity.
Methods
U. lobata leaf was extracted in hot water and ...
Diabetic gangrene is a complication of Diabetes mellitus caused by Staphylococcus aureus. The combination of Ceftriaxone and Chloramphenicol is often used to cure gangrene infection, even though, they produce antagonist ...
Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A(International Journal of Pharmacognosy and Phytochemical research (IJPPR), 2015-01-19)
Glucagon Like Peptide-1 (GLP-1) is one of incretin hormone which is proposed as a new therapy for type 2 diabetes
(T2DM). However, this hormone is metabolized excessively by Dipeptidyl Peptidase IV (DPP-IV) into inactive ...
Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, Moch Aris(Medicinal Plants - International Journal of Phytomedicines and Related Industries, 2018-05-28)
This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ...
Purnomo, Yudi; Pamungkas, Iqbal A; Sofiani, Mita; Pratama, Sumanjaya(Tropical Journal of Natural Product Research (TJNPR), 2021-06-01)
Pulutan (Urena lobata) is a medicinal plant having antioxidant activity. However, their potency to inhibit the adverse effects of malathion has not been evaluated. The study aims to examine Urena lobata (U. lobata) leaves ...
Purnomo, Yudi; Taufiq, Muhammad; Wijaya, Afnan N. D.; Hakim, Reza(Tropical Journal of Natural Product Research, 2021-10-01)
Dipeptidyl Peptidase-4 (DPP-4) and alpha-glucosidase (α-glucosidase) are enzymes involved in carbohydrate metabolism. Inhibition of these enzymes contribute to blood glucose level suppression. Soybean (Glycine max) seeds ...
Purnomo, Yudi; Triliana, Rahma; Wibisono, Nugroho(Tropical Journal of Natural Product Research (TJNPR), 2022-05-12)
Diabetes mellitus (DM) is linked to an increase in dyslipidemia, which is associated with atherosclerosis, one of the leading causes of cardiovascular disease. Soybean(Glycine max) and ginger(Zingiber officinale) ...
Purnomo, Yudi; Makdasari, Juliah; Inayah Fatahillah, Faiqoh(Journal of Basic and Clinical Physiology and Pharmacology, 2021-11-21)
In food ingestion, alpha-glucosidase (α-glucosidase) and alpha-amylase (α-amylase) are enzymes that are responsible to convert a carbohydrate into glucose. Inhibition of both enzyme activities can prolong absorption of ...
Yang, Dongqing; Anderson, Paul H.; Wijeyanaka, Asiri R.; Barratt, Kate R.; Triliana, Rahma; Stapledon, Catherine J.M.; Zhou, Hong; Findlay, David M.; Morris, Howard A.; Atkins, Gerald J.(Elsevier, 2018)
Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ...
Wahyuningrum, Ike; Hariyadi, D. M; Hendradi, E(MRI Publications Lucknow, Uttar Pradesh, India, 2017-04-20)
Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains
solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC ...
Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation
of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown
to have anti-inflammatory and antioxidant ...
Widyaningrum, Ike; Wibisono, Nugroho; Kusumawati, Anggun Hari(International journal of Health & Medical Sciences, 2020-10-18)
This study aims to compare the antibacterial activity of Staphylococcus aureus from tapak liman leaf
extract using different extraction methods, maceration, and soxhletation. Maceration is a type of cold extraction, ...
Background: Atopic dermatitis is a chronic, recurrent inflammation
of the skin, accompanied by severe pruritus. Immune system
dysregulation and skin barrier defects are associated with the
abnormalities in atopic ...
Sulistyowati, Erna; Permatasari, Nur; Widodo, M Aris(Elsevier, 2017-06-07)
Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin.
Methods: After ...
Sulistyowati, Erna; Hsu, Jong-Hau; Cheng, Yuan-Bin; Chang, Fang-Rong; Cheng, Ying-Fu; Yeh, Jwu-Lai(US National Library of Medicine National Institutes of Health, 2017-09-30)
Indonesian herbal medicine Centella asiatica, Justicia gendarussa and
Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension.
Oxidative stress plays an important role in hypertension-induced ...