• HUBUNGAN KUANTITATIF STRUKTUR-PROPERTI (HKSP) SENYAWA AKTIF TEMU KUNCI (BOESENBERGIA PANDURATA) SEBAGAI PENGHAMBAT ENZIM MAIN PROTEASE (MPRO) SARS-CoV-2 

  Widiyana, Anita Puspa (Sanata Dharma University Press, 2022-12-10)

  Hubungan parameter fisikokimia dari 15 senyawa aktif Boesenbergia pandurata dalam menghambat enzim main protease SARS-CoV-2 diprediksi melalui model Hubungan Kuantitatif Struktur-Properti (HKSP). Semua senyawa aktif ...

• EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP KADAR SOD DAN MDA PADA AORTA TIKUS MODEL DIABETES MELITUS TIPE 2 

  Purnomo, Yudi; Putra Sanjaya, Hendra; Annis Pramesti, Fathia (Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-03-01)

  Hiperglikemia pada diabetes melitus (DM) meningkatkan produksi reactive oxygen species (ROS) yang berperan terhadap komplikasi makroangiopati diabetik. Daun gedi merah dikenal memiliki efek antioksidan dan antihiperglikemia ...

• EFEK EKSTRAK ETANOL DAUN GEDI MERAH (ABELMOSCHUS MANIHOT (L.) MEDIK) TERHADAP KADAR SUPEROXIDE DISMUTASE DAN MALONDIALDEHYDE JARINGAN GINJAL TIKUS MODEL DIABETES MELITUS TIPE 2 

  Purnomo, Yudi; Fuadi, Ahmad; Arif Martino, Yoyon (Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-09-12)

  Hiperglikemia pada Diabetes Melitus (DM) meningkatkan produksi Reactive Oxygen Species (ROS) dan berperan terhadap risiko komplikasi nefropati diabetik. Daun gedi merah (Abelmoschus manihot (L.) Medik) berkhasiat sebagai ...

• EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP PERSENTASE INTERLEUKIN-10 (IL-10) DAN SEL T SITOTOKSIK (CD8+ ) TIKUS MODEL DIABETES Tipe II 

  Purnomo, Yudi; Kamilah, Nur; Hakim, Reza (Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2019-03-01)

  Inflamasi akibat kerusakan oksidatif yang dipicu hiperglikemia berperan terhadap progresivitas diabetes melitus (DM). Interleukin-10 (IL-10) dan CD8+ berpengaruh terhadap proses inflamasi. Abelmoschus manihot (L.) Medik ...

• In Silico Study of Pulutan (Urena lobata) Leaf Extract as Anti Inflammation and their ADME Prediction 

  Wahyuningsih, Doti; Purnomo, Yudi; Tilaqza, Andri (Journal of Tropical Pharmacy and Chemistry (JTPC), 2022-06-30)

  Inflammation is the basic for the pathogenesis of several diseases both of degenerative and non-degenerative disease. Urena lobata is a medicinal plant that can be found in Indonesia and has been used traditionally to cure ...

• Analisa Kelengkapan dan Kesesuaian Peresepan Pasien Rawat Jalan di Rumah Sakit Islam “X” Malang 

  Purnomo, Yudi; Rejeki, Wara (Journal of Pharmaceutical Care Anwar Medika (JPhAM), 2022-07-04)

  Peresepan obat yang tidak rasional merupakan masalah serius dalam pelayanan kesehatandi Indonesia. Faktor yang berperan terhadap kondisi ini adalah ketidaklengkapan dan ketidaksesuaian peresepan ...

• Potensi Toleransi Oral Glukosa Ekstrak Biji Kedelai (Glycine Max), Rimpang Jahe (Zingiber Officinale) Dan Kombinasinya Pada Tikus Model Diabetes 

  Purnomo, Yudi (Jurnal Kesehatan Islam (JKI), 2018-09-20)

  Diabetes Mellitus (DM) adalah sindrom metabolik yang ditandai peningkatan kadar glukosa darah kronik dan berkontribusi terhadap beberapa resiko komplikasi. Biji Kedelai(G.max) danrimpang Jahe (Z.officinale) digunakan sebagai ...

• Anti-diabetic potential of Urena lobata leaf extract through inhibition of dipeptidyl peptidase IV activity 

  Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A (Asian Pacific Journal of Tropical Biomedicine, 2015-08-01)

  Objective To evaluate the anti-diabetic potential of leaf extract from Urena lobata (U. lobata) through dipeptidyl peptidase IV (DPP-IV) inhibitory activity. Methods U. lobata leaf was extracted in hot water and ...

• EFEK KOMBINASI SEFTRIAKSON DAN KLORAMFENIKOL PADA Staphylococcus aureus DARI ISOLAT GANGREN DIABETIK 

  Purnomo, Yudi; Chandra, Pasha; Triliana, Rahma (Jurnal Farmasi Galenika, 2022-03-01)

  Diabetic gangrene is a complication of Diabetes mellitus caused by Staphylococcus aureus. The combination of Ceftriaxone and Chloramphenicol is often used to cure gangrene infection, even though, they produce antagonist ...

• Anti-hiperglycemic Effect of Urena lobata Leaf Extract by Inhibition of Dipeptidyl Peptidase IV ( DPP-IV ) on Diabetic Rats 

  Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A (International Journal of Pharmacognosy and Phytochemical research (IJPPR), 2015-01-19)

  Glucagon Like Peptide-1 (GLP-1) is one of incretin hormone which is proposed as a new therapy for type 2 diabetes (T2DM). However, this hormone is metabolized excessively by Dipeptidyl Peptidase IV (DPP-IV) into inactive ...

• Inhibitory activity of Urena lobata leaf extract on dipeptidyl peptidase-4 (DPP-4): Is it different in vitro and in vivo? 

  Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, Moch Aris (Medicinal Plants - International Journal of Phytomedicines and Related Industries, 2018-05-28)

  This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ...

• Effect of Pulutan (Urena lobata) Leaf Extract on Blood Glucose Level, Hemoglobin and Body Growth of Zebra Fish (Danio rerio) Exposed to Malathion 

  Purnomo, Yudi; Pamungkas, Iqbal A; Sofiani, Mita; Pratama, Sumanjaya (Tropical Journal of Natural Product Research (TJNPR), 2021-06-01)

  Pulutan (Urena lobata) is a medicinal plant having antioxidant activity. However, their potency to inhibit the adverse effects of malathion has not been evaluated. The study aims to examine Urena lobata (U. lobata) leaves ...

• Molecular Docking of Soybean (Glycine max) Seed and Ginger (Zingiber officinale) Rhizome Components as Anti-Diabetic Through Inhibition of Dipeptidyl Peptidase 4 (DPP-4) and Alpha-Glucosidase Enzymes 

  Purnomo, Yudi; Taufiq, Muhammad; Wijaya, Afnan N. D.; Hakim, Reza (Tropical Journal of Natural Product Research, 2021-10-01)

  Dipeptidyl Peptidase-4 (DPP-4) and alpha-glucosidase (α-glucosidase) are enzymes involved in carbohydrate metabolism. Inhibition of these enzymes contribute to blood glucose level suppression. Soybean (Glycine max) seeds ...

• Anti-atherogenic Effects of Soybean (Glycine max) Seed and Ginger (Zingiber officinale) Rhizome Extracts on Type 2 Diabetic Rat Model 

  Purnomo, Yudi; Triliana, Rahma; Wibisono, Nugroho (Tropical Journal of Natural Product Research (TJNPR), 2022-05-12)

  Diabetes mellitus (DM) is linked to an increase in dyslipidemia, which is associated with atherosclerosis, one of the leading causes of cardiovascular disease. Soybean(Glycine max) and ginger(Zingiber officinale) ...

• Inhibitory activity of Urena lobata leaf extract on alpha-amylase and alpha-glucosidase: in vitro and in silico approach 

  Purnomo, Yudi; Makdasari, Juliah; Inayah Fatahillah, Faiqoh (Journal of Basic and Clinical Physiology and Pharmacology, 2021-11-21)

  In food ingestion, alpha-glucosidase (α-glucosidase) and alpha-amylase (α-amylase) are enzymes that are responsible to convert a carbohydrate into glucose. Inhibition of both enzyme activities can prolong absorption of ...

• Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation 

  Yang, Dongqing; Anderson, Paul H.; Wijeyanaka, Asiri R.; Barratt, Kate R.; Triliana, Rahma; Stapledon, Catherine J.M.; Zhou, Hong; Findlay, David M.; Morris, Howard A.; Atkins, Gerald J. (Elsevier, 2018)

  Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ...

• Cardiovascular protective effect of Indonesian herbal medicine in spontaneously hypertensive rats 

  Yeh, Jwu-Lai; Sulistyowati, Erna (J-STAGE, 2018)

• Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo 

  Wahyuningrum, Ike; Hariyadi, D. M; Hendradi, E (MRI Publications Lucknow, Uttar Pradesh, India, 2017-04-20)

  Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC ...

• In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis 

  Huang, Shang-En; Sulistyowati, Erna; Chao, Yu-Ying; Wu, Bin-Nan; Dai, Zen-Kong; Hsu, Jong-Hau; Yeh, Jwu-Lai (National Library of Medicine, 2021-05-28)

  Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ...

• Effect of Extraction Method on Antimicrobial Activity Against Staphylococcus Aureus of Tapak Liman (Elephantopus Scaber L.) Leaves 

  Widyaningrum, Ike; Wibisono, Nugroho; Kusumawati, Anggun Hari (International journal of Health & Medical Sciences, 2020-10-18)

  This study aims to compare the antibacterial activity of Staphylococcus aureus from tapak liman leaf extract using different extraction methods, maceration, and soxhletation. Maceration is a type of cold extraction, ...

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