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Browsing LP - Pharmaceutical by Title
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Purnomo, Yudi; Aini, Noer; Widodo, Aris Moch
(The Japanese Pharmacological Society, The Japanese Society of Clinical Pharmacology, 2018-07-06)
Pulutan (Urena lobata) is medicinal plant used to treat some diseases empirically, with pre-clinical study has already proven its efficacy, however, its safety has not been evaluated. Acute toxicity has to be performed on ...
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Purnomo, Yudi; Rejeki, Wara
(Journal of Pharmaceutical Care Anwar Medika (JPhAM), 2022-07-04)
Peresepan obat yang tidak rasional merupakan masalah serius dalam pelayanan kesehatandi Indonesia. Faktor yang berperan terhadap kondisi ini adalah ketidaklengkapan dan ketidaksesuaian peresepan ...
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Purnomo, Yudi; Triliana, Rahma; Wibisono, Nugroho
(Tropical Journal of Natural Product Research (TJNPR), 2022-05-12)
Diabetes mellitus (DM) is linked to an increase in dyslipidemia, which is associated with atherosclerosis, one of the leading causes of cardiovascular disease. Soybean(Glycine max) and ginger(Zingiber officinale) ...
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Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A
(Asian Pacific Journal of Tropical Biomedicine, 2015-08-01)
Objective
To evaluate the anti-diabetic potential of leaf extract from Urena lobata (U. lobata) through dipeptidyl peptidase IV (DPP-IV) inhibitory activity.
Methods
U. lobata leaf was extracted in hot water and ...
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Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A
(International Journal of Pharmacognosy and Phytochemical research (IJPPR), 2015-01-19)
Glucagon Like Peptide-1 (GLP-1) is one of incretin hormone which is proposed as a new therapy for type 2 diabetes
(T2DM). However, this hormone is metabolized excessively by Dipeptidyl Peptidase IV (DPP-IV) into inactive ...
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Wahyuningrum, Ike; Hariyadi, D. M; Hendradi, E
(MRI Publications Lucknow, Uttar Pradesh, India, 2017-04-20)
Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains
solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC ...
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Wahyuningsih, Doti; Purnomo, Yudi
(Jurnal Universitas Brawijaya, 2018-02-20)
Chronic hyperglycemia is one of the signs of human type-2 diabetes mellitus due to insulin resistance and depletion. This study aimed to evaluate hexane, ethanolic, and aqueous leaf extracts of Urena lobata as antihyperglycemic ...
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Widiyana, Anita P; Putra, Galih S; Muclashi, Luthfi A
(Fakultas Farmasi Universitas Airlangga, 2016-12-02)
Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein
targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ...
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Wulandari, Dian N; Nugraha, Jusak; Soedarsono, Soedarsono
(Lembaga Penyakit Tropis (Institute of Tropical Disease) Universitas Airlangga, 2018-04-01)
M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be ...
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Purnomo, Yudi; Putra Sanjaya, Hendra; Annis Pramesti, Fathia
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-03-01)
Hiperglikemia pada diabetes melitus (DM) meningkatkan produksi reactive oxygen species (ROS)
yang berperan terhadap komplikasi makroangiopati diabetik. Daun gedi merah dikenal memiliki efek antioksidan
dan antihiperglikemia ...
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Purnomo, Yudi; Fuadi, Ahmad; Arif Martino, Yoyon
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-09-12)
Hiperglikemia pada Diabetes Melitus (DM) meningkatkan produksi Reactive Oxygen Species
(ROS) dan berperan terhadap risiko komplikasi nefropati diabetik. Daun gedi merah (Abelmoschus manihot (L.)
Medik) berkhasiat sebagai ...
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Purnomo, Yudi; Kamilah, Nur; Hakim, Reza
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2019-03-01)
Inflamasi akibat kerusakan oksidatif yang dipicu hiperglikemia berperan terhadap progresivitas
diabetes melitus (DM). Interleukin-10 (IL-10) dan CD8+ berpengaruh terhadap proses inflamasi. Abelmoschus
manihot (L.) Medik ...
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Purnomo, Yudi; Chandra, Pasha; Triliana, Rahma
(Jurnal Farmasi Galenika, 2022-03-01)
Diabetic gangrene is a complication of Diabetes mellitus caused by Staphylococcus aureus. The combination of Ceftriaxone and Chloramphenicol is often used to cure gangrene infection, even though, they produce antagonist ...
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Purnomo, Yudi; Soeatmadji, Djoko W; Widodo, M Aris
(Russian Open Medical Journal, 2019-05-28)
Aim — To evaluate the effect of ascorbic acid, α-tocopherol, and its combination on the permeability of human umbilical vein
endothelial cells (HUVEC’S) culture after high glucose concentration exposure.
Material and ...
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Widyaningrum, Ike; Wibisono, Nugroho; Kusumawati, Anggun Hari
(International journal of Health & Medical Sciences, 2020-10-18)
This study aims to compare the antibacterial activity of Staphylococcus aureus from tapak liman leaf
extract using different extraction methods, maceration, and soxhletation. Maceration is a type of cold extraction, ...
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Purnomo, Yudi; Pamungkas, Iqbal A; Sofiani, Mita; Pratama, Sumanjaya
(Tropical Journal of Natural Product Research (TJNPR), 2021-06-01)
Pulutan (Urena lobata) is a medicinal plant having antioxidant activity. However, their potency to inhibit the adverse effects of malathion has not been evaluated. The study aims to examine Urena lobata (U. lobata) leaves ...
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Andrajati, Retnosari; Tilaqza, Andri; Supardi, Sudibyo
(Elsevier, 2016-01-12)
Irrational antibiotic prescription is common in developing countries, including in Indonesia. The aims of this study were to evaluate antibiotic prescription patterns and the factors related to the rationale for antibiotic ...
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Kusumawati, Anggun Hari; Yonathan, Kesya; Ridwanuloh, Dadan; Widyaningrum, Ike
(Fakultas Farmasi, Universitas Buana Perjuangan Karawang, 2020-05-09)
Kulit yang sehat dapat mencerminkan kesehatan seseorang. Menjadikan kulit sehat, bersih dan cerah merupakan idaman semua orang terutama pada wanita. Antioksidan melindungi tubuh dari kerusakan yang disebabkan oleh radikal ...
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Wahyuningsih, Doti; Purnomo, Yudi; Tilaqza, Andri
(Journal of Tropical Pharmacy and Chemistry (JTPC), 2022-06-30)
Inflammation is the basic for the pathogenesis of several diseases both of degenerative and non-degenerative disease. Urena lobata is a medicinal plant that can be found in Indonesia and has been used traditionally to cure ...
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Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A
(Elsevier, 2017-07-20)
This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test ...