Browsing LP - Faculty of Medicine by Title
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Acute Toxicity Level of Pulutan (Urena lobata) Leaf Extract on Zebrafish (Danio rerio) and its Analysis by In Silico Study
(The Japanese Pharmacological Society, The Japanese Society of Clinical Pharmacology, 2018-07-06)Pulutan (Urena lobata) is medicinal plant used to treat some diseases empirically, with pre-clinical study has already proven its efficacy, however, its safety has not been evaluated. Acute toxicity has to be performed on ... -
Analisa Kelengkapan dan Kesesuaian Peresepan Pasien Rawat Jalan di Rumah Sakit Islam “X” Malang
(Journal of Pharmaceutical Care Anwar Medika (JPhAM), 2022-07-04)Peresepan obat yang tidak rasional merupakan masalah serius dalam pelayanan kesehatandi Indonesia. Faktor yang berperan terhadap kondisi ini adalah ketidaklengkapan dan ketidaksesuaian peresepan ... -
Anti-atherogenic Effects of Soybean (Glycine max) Seed and Ginger (Zingiber officinale) Rhizome Extracts on Type 2 Diabetic Rat Model
(Tropical Journal of Natural Product Research (TJNPR), 2022-05-12)Diabetes mellitus (DM) is linked to an increase in dyslipidemia, which is associated with atherosclerosis, one of the leading causes of cardiovascular disease. Soybean(Glycine max) and ginger(Zingiber officinale) ... -
Anti-diabetic potential of Urena lobata leaf extract through inhibition of dipeptidyl peptidase IV activity
(Asian Pacific Journal of Tropical Biomedicine, 2015-08-01)Objective To evaluate the anti-diabetic potential of leaf extract from Urena lobata (U. lobata) through dipeptidyl peptidase IV (DPP-IV) inhibitory activity. Methods U. lobata leaf was extracted in hot water and ... -
Anti-hiperglycemic Effect of Urena lobata Leaf Extract by Inhibition of Dipeptidyl Peptidase IV ( DPP-IV ) on Diabetic Rats
(International Journal of Pharmacognosy and Phytochemical research (IJPPR), 2015-01-19)Glucagon Like Peptide-1 (GLP-1) is one of incretin hormone which is proposed as a new therapy for type 2 diabetes (T2DM). However, this hormone is metabolized excessively by Dipeptidyl Peptidase IV (DPP-IV) into inactive ... -
Anti-Inflammatory Activity of Agaricus Blazei Murill Extract In The Spleen of Mice Fed a High-Fat Diet
(Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria, 2018-03-31)urpose: To examine the effects of A. blazei Murill on the production of proinflammatory cytokine TNF-α and regulatory cytokine IL-10 in the spleen of mice fed a high-fat diet. Methods: The study was conducted on 25 BALB/c ... -
Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo
(MRI Publications Lucknow, Uttar Pradesh, India, 2017-04-20)Objective: The aim of this research study was to investigate the anti-inflammatory effect of NLC meloxicam. NLC contains solid and liquid lipid. Monostearin as solid lipid and Miglyol 808 as liquid lipid. Methods : NLC ... -
Antidiabetic Effect of Urena lobata: Preliminary Study on Hexane, Ethanolic, and Aqueous Leaf Extracts
(Jurnal Universitas Brawijaya, 2018-02-20)Chronic hyperglycemia is one of the signs of human type-2 diabetes mellitus due to insulin resistance and depletion. This study aimed to evaluate hexane, ethanolic, and aqueous leaf extracts of Urena lobata as antihyperglycemic ... -
Association of LL-37 and IL-31 Serum Levels with SCORing Atopic Dermatitis (SCORAD) Score in Atopic Dermatitis Patients
(Iranian Journal of Dermatology, 2018-05-12)Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic ... -
Atheroprotective Effect of The Agaricus Blazei Mur ill Extract in High Fat Diet-Induced Mice
(Medicinal Plants, 2017-02-20)The purpose of the present study was to provide evidence of the potential of Agaricus blazei Murill extract as atheroprotective agent. The study was conducted with 25 male mice (Mus musculus) divided into f ive groups ... -
Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation
(Elsevier, 2018)Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ... -
Combined Effects of Shear Stress and Glucose on the Morphology, Actin Filaments, and VE-Cadherin of Endothelial Cells in Vitro
(Elsevier, 2017-06-07)Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin. Methods: After ... -
Comparison of DNA Extraction Methods Between Conventional, Kit, Alkali and Buffer-Only for PCR Amplification on Raw and Boiled Bovine and Porcine Meat
(Universitas Brawijaya, 2017)Detection of porcine contamination in food material by employing PCR techniques is integral in halal food confirmation. However, PCR is both costly and laborious, particularly in DNA isolation method. This study explores ... -
Design and Molecular Docking Studies of Quinazoline Derivatives as Antiproliferation
(Fakultas Farmasi Universitas Airlangga, 2016-12-02)Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ... -
Dietary Ethanolic Extract of Mangosteen pericarp Reduces VCAM-1, Perivascular Adipose Tissue and Aortic Intimal Medial Thickness in Hypercholesterolemic Rat Model
(US National Library of Medicine National Institutes of Health, 2019-10-10)BACKGROUND: High-fat diet (HFD) is associated with dyslipidemia which is a risk factor for atherosclerosis. Dyslipidemia causes oxidative stress which induces vascular cell adhesion molecule-1 (VCAM-1). Oxidative stress ... -
The difference of map1lc3 level as macrophage autophagy Marker between resistant and sensitive tuberculosis patients on rifampicin
(Lembaga Penyakit Tropis (Institute of Tropical Disease) Universitas Airlangga, 2018-04-01)M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP KADAR SOD DAN MDA PADA AORTA TIKUS MODEL DIABETES MELITUS TIPE 2
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-03-01)Hiperglikemia pada diabetes melitus (DM) meningkatkan produksi reactive oxygen species (ROS) yang berperan terhadap komplikasi makroangiopati diabetik. Daun gedi merah dikenal memiliki efek antioksidan dan antihiperglikemia ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (ABELMOSCHUS MANIHOT (L.) MEDIK) TERHADAP KADAR SUPEROXIDE DISMUTASE DAN MALONDIALDEHYDE JARINGAN GINJAL TIKUS MODEL DIABETES MELITUS TIPE 2
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-09-12)Hiperglikemia pada Diabetes Melitus (DM) meningkatkan produksi Reactive Oxygen Species (ROS) dan berperan terhadap risiko komplikasi nefropati diabetik. Daun gedi merah (Abelmoschus manihot (L.) Medik) berkhasiat sebagai ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP PERSENTASE INTERLEUKIN-10 (IL-10) DAN SEL T SITOTOKSIK (CD8+ ) TIKUS MODEL DIABETES Tipe II
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2019-03-01)Inflamasi akibat kerusakan oksidatif yang dipicu hiperglikemia berperan terhadap progresivitas diabetes melitus (DM). Interleukin-10 (IL-10) dan CD8+ berpengaruh terhadap proses inflamasi. Abelmoschus manihot (L.) Medik ...