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Browsing LP - Pharmaceutical by Title
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Wahyuningsih, Doti; Purnomo, Yudi
(Jurnal Universitas Brawijaya, 2018-02-20)
Chronic hyperglycemia is one of the signs of human type-2 diabetes mellitus due to insulin resistance and depletion. This study aimed to evaluate hexane, ethanolic, and aqueous leaf extracts of Urena lobata as antihyperglycemic ...
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Widiyana, Anita P; Putra, Galih S; Muclashi, Luthfi A
(Fakultas Farmasi Universitas Airlangga, 2016-12-02)
Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein
targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ...
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Wulandari, Dian N; Nugraha, Jusak; Soedarsono, Soedarsono
(Lembaga Penyakit Tropis (Institute of Tropical Disease) Universitas Airlangga, 2018-04-01)
M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be ...
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Purnomo, Yudi; Putra Sanjaya, Hendra; Annis Pramesti, Fathia
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-03-01)
Hiperglikemia pada diabetes melitus (DM) meningkatkan produksi reactive oxygen species (ROS)
yang berperan terhadap komplikasi makroangiopati diabetik. Daun gedi merah dikenal memiliki efek antioksidan
dan antihiperglikemia ...
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Purnomo, Yudi; Fuadi, Ahmad; Arif Martino, Yoyon
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-09-12)
Hiperglikemia pada Diabetes Melitus (DM) meningkatkan produksi Reactive Oxygen Species
(ROS) dan berperan terhadap risiko komplikasi nefropati diabetik. Daun gedi merah (Abelmoschus manihot (L.)
Medik) berkhasiat sebagai ...
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Purnomo, Yudi; Kamilah, Nur; Hakim, Reza
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2019-03-01)
Inflamasi akibat kerusakan oksidatif yang dipicu hiperglikemia berperan terhadap progresivitas
diabetes melitus (DM). Interleukin-10 (IL-10) dan CD8+ berpengaruh terhadap proses inflamasi. Abelmoschus
manihot (L.) Medik ...
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Purnomo, Yudi; Chandra, Pasha; Triliana, Rahma
(Jurnal Farmasi Galenika, 2022-03-01)
Diabetic gangrene is a complication of Diabetes mellitus caused by Staphylococcus aureus. The combination of Ceftriaxone and Chloramphenicol is often used to cure gangrene infection, even though, they produce antagonist ...
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Purnomo, Yudi; Soeatmadji, Djoko W; Widodo, M Aris
(Russian Open Medical Journal, 2019-05-28)
Aim — To evaluate the effect of ascorbic acid, α-tocopherol, and its combination on the permeability of human umbilical vein
endothelial cells (HUVEC’S) culture after high glucose concentration exposure.
Material and ...
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Widyaningrum, Ike; Wibisono, Nugroho; Kusumawati, Anggun Hari
(International journal of Health & Medical Sciences, 2020-10-18)
This study aims to compare the antibacterial activity of Staphylococcus aureus from tapak liman leaf
extract using different extraction methods, maceration, and soxhletation. Maceration is a type of cold extraction, ...
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Purnomo, Yudi; Pamungkas, Iqbal A; Sofiani, Mita; Pratama, Sumanjaya
(Tropical Journal of Natural Product Research (TJNPR), 2021-06-01)
Pulutan (Urena lobata) is a medicinal plant having antioxidant activity. However, their potency to inhibit the adverse effects of malathion has not been evaluated. The study aims to examine Urena lobata (U. lobata) leaves ...
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Andrajati, Retnosari; Tilaqza, Andri; Supardi, Sudibyo
(Elsevier, 2016-01-12)
Irrational antibiotic prescription is common in developing countries, including in Indonesia. The aims of this study were to evaluate antibiotic prescription patterns and the factors related to the rationale for antibiotic ...
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Kusumawati, Anggun Hari; Yonathan, Kesya; Ridwanuloh, Dadan; Widyaningrum, Ike
(Fakultas Farmasi, Universitas Buana Perjuangan Karawang, 2020-05-09)
Kulit yang sehat dapat mencerminkan kesehatan seseorang. Menjadikan kulit sehat, bersih dan cerah merupakan idaman semua orang terutama pada wanita. Antioksidan melindungi tubuh dari kerusakan yang disebabkan oleh radikal ...
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Wahyuningsih, Doti; Purnomo, Yudi; Tilaqza, Andri
(Journal of Tropical Pharmacy and Chemistry (JTPC), 2022-06-30)
Inflammation is the basic for the pathogenesis of several diseases both of degenerative and non-degenerative disease. Urena lobata is a medicinal plant that can be found in Indonesia and has been used traditionally to cure ...
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Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, M.A
(Elsevier, 2017-07-20)
This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test ...
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Putra, Galih S; Widiyana, Anita P; Muchlashi, Luthfi A; Sulistyowati, Mellany I; Ekowati, Juni; Budiati, Tutuk
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)
The aim of this research was to compare the effect of pyridine and triethylamine catalyst ratios on the
synthesis of 2-phenyl-benzo(d)[1,3] oxazine-4-one derivatives. The catalysts used were triethylene amine
(100%), ...
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Purnomo, Yudi; Makdasari, Juliah; Inayah Fatahillah, Faiqoh
(Journal of Basic and Clinical Physiology and Pharmacology, 2021-11-21)
In food ingestion, alpha-glucosidase (α-glucosidase) and alpha-amylase (α-amylase) are enzymes that are responsible to convert a carbohydrate into glucose. Inhibition of both enzyme activities can prolong absorption of ...
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Yudi, Purnomo; Djoko, Soeatmadji; Bambang, Sumitro Sutiman; Aris, Widodo Moch
(Society For Conservation And Resource Development Of Medicinal Plants, 2018-05-25)
This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ...
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Purnomo, Yudi; Soeatmadji, D.W; Sumitro, S.B; Widodo, Moch Aris
(Medicinal Plants - International Journal of Phytomedicines and Related Industries, 2018-05-28)
This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ...
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Purnomo, Yudi; Taufiq, Muhammad; Wijaya, Afnan N. D.; Hakim, Reza
(Tropical Journal of Natural Product Research, 2021-10-01)
Dipeptidyl Peptidase-4 (DPP-4) and alpha-glucosidase (α-glucosidase) are enzymes involved in carbohydrate metabolism. Inhibition of these enzymes contribute to blood glucose level suppression. Soybean (Glycine max) seeds ...
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Purnomo, Yudi
(Jurnal Kesehatan Islam (JKI), 2018-09-20)
Diabetes Mellitus (DM) adalah sindrom metabolik yang ditandai peningkatan kadar glukosa darah kronik dan berkontribusi terhadap beberapa resiko komplikasi. Biji Kedelai(G.max) danrimpang Jahe (Z.officinale) digunakan sebagai ...