LP - Faculty of Medicine: Recent submissions

Now showing items 21-40 of 61

Vasculoprotective Effects of Centella Asiatica, Justicia Gendarussa and Imperata Cylindrica Decoction via the NOXs-ROS-NF-κB Pathway in Spontaneously Hypertensive Rats

Sulistyowati, Erna; Jan, Ren-Long; Liou, Shu-Fen; Chen, Ying-Fu; Wu, Bin-Nan; Hsu, Jong-Hau; Yeh, Jwu-Lai (Elsevier, 2019-06-24)

Background and aim: Centella asiatica,Justicia gendarussaandImperata cylindricadecoction (CJID) isefficacious for hypertension. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-induced reactive oxygen ...
Association of LL-37 and IL-31 Serum Levels with SCORing Atopic Dermatitis (SCORAD) Score in Atopic Dermatitis Patients

Brahmanti, Herwinda; Rofiq, Aunur; Cholis, Moch; Trijayanti, Unundya; Purwanti, Sasi (Iranian Journal of Dermatology, 2018-05-12)

Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic ...
Combined Effects of Shear Stress and Glucose on the Morphology, Actin Filaments, and VE-Cadherin of Endothelial Cells in Vitro

Sulistyowati, Erna; Permatasari, Nur; Widodo, M Aris (Elsevier, 2017-06-07)

Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin. Methods: After ...
Indonesian Herbal Medicine Prevents Hypertension-Induced Left Ventricular Hypertrophy by Diminishing NADPH Oxidase-Dependent Oxidative Stress

Sulistyowati, Erna; Hsu, Jong-Hau; Cheng, Yuan-Bin; Chang, Fang-Rong; Cheng, Ying-Fu; Yeh, Jwu-Lai (US National Library of Medicine National Institutes of Health, 2017-09-30)

Indonesian herbal medicine Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension. Oxidative stress plays an important role in hypertension-induced ...
The Interaction of β-Glucan on Dectin-1 Receptor or TLR-2 Might Have the Potency to Activate Function of Treg Cell and Production of Anti-Inflammatory Cytokine

Kurniawan, Dicky; Sargowo, Djanggan; Tjokroprawiro, Askandar; Rifa'i, Muhaimin (EurAsian Journal of BioSciences, 2020-03-20)

Objectives: Atherosclerosis formed due to the accumulation of the fibrous tissues in the vascular wall and gradually become thrombus. Agaricus brasiliensis known as a traditional drug for lifestylerelated diseases, including ...
The Prophylactic Effects of Pomegranate Peel in a Rat Model of Rheumatoid Arthritis: Study on Arthritis Score and Expression of Inflammatory Markers

Wahyuningsih, Doti; Amalia, Annisa; Amiruddin, Meilano Setiawan; Cahyaningrum, Asri; Kurniasari, Laili Chintianur (Jurnal Universitas Brawijaya, 2020)

Rheumatoid arthritis (RA) is a joint disease, chronically cause permanent joint impairment leading to inability of daily life activities. Early diagnosis and preven tive managements of RA are recommended to overcome the ...
The Potency of Soursop Leaf Water Extract on Activating GLP-1R, Inhibiting DPP4 And FoxO1 Protein Based on in Silico Analysis

Damayanti, Dini Sri; Nurdiana; Kusuma, Chandra; Soeadmadji, Djoko Wahono (International Journal of Applied Pharmaceutics, 2019-12-15)

Objective: Soursop leaf contains alkaloids, terpenoids, flavonoids, acetogenin, and phenolics. Soursop leaf decoction is usually consumed as an anti obesity agent, even though its active compounds and its action mechanism ...
Study of Superoxide Dismutase and Malondialdehyde Concentrations in Mice After Administration of Methanolic Extract of Scurrula Atropurpurea (BL.)

Athiro, Nour; Wahyuningsih, Doti (Fakultas Kedokteran Hewan, Universitas Syiah Kuala, 2017-03)

The aim of this research was to investigate the potential effect of methanolic extract of Scurrula atropurpurea (MESA) in reducing oxidative stress through observation of superoxide dismutase (SOD) activity and malondialdehyde ...
Perbedaan Ekspresi Protein Cyclin D1 antara Adenoma dan Adenokarsinoma Kolorektal, serta Korelasinya dengan Grading dan Stadium Tumor

Rosidah, Aris; Norahmawati, Eviana; Anita, Kenty Wanty; Rasyid, Harun Al (Fakultas Kedokteran Universitas Brawijaya, 2020-03-20)

Sebagian besar karsinoma kolorektal adalah adenokarsinoma, dan lebih dari 95% karsinoma kolorektal diawali oleh lesi prekursor yaitu adenoma. Risiko suatu adenoma berubah menjadi suatu karsinoma akan lebih tinggi pada ...
Korelasi IgE Terhadap Rasio Neutrofil/Eosinofil Jaringan dan Darah Penderita Rinosinusitis Kronik Aspergillus Fumigatus

Duhitatrissari, Fifin Pradina; Retnoningsih, Endang; Maharani, Iriana (Oto Rhino Laryngologica Indonesiana, 2018-06-01)

Latar Belakang: Prevalensi rinosinusitis kronik (RSK) jamur saat ini cenderung meningkat. Jamur berperan sebagai mikroorganisme dan merupakan salah satu penyebab RSK. Pemeriksaan immunoglobulin E (IgE) Aspergillus ...
Profile of Patients with Floaters in Saiful Anwar Hospital Malang

Hidayah, Fenti Kusumawardhani; Dewi, Nadia Artha; Refa, Safaruddin (Indonesian Vitreoretinal Society, 2018-08-24)

Introduction: To report the profile of patients with floaters as a subjective complain in Saiful Anwar Hospital from July 2012 until June 2013. Methods: an observasional descriptive study was conducted, collecting data ...
Metode Slow Sand Filter dan Pengukuran MPN Coliform Sebagai Upaya Peningkatan Kualitas Air Sungai di Pekapuran Raya Banjarmasin

Herlina, Sri (Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018)

Sungai Pekapuran Raya Banjarmasin merupakan salah satu kawasan pinggiran sungai yang padat penduduk, saat musim kemarau kondisi sungai terlihat dangkal dipenuhi tumpukan sampah, berwarna kecoklatan dan keruh. Penelitian ...
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

Lee, Meng-Luen; Sulistyowati, Erna; Hsu, Jong-Hau; Huang, Bo-Yau; Dai, Zen-Kong; Wu, Bin-Nan; Chao, Yu-Ying; Yeh, Jwu-Lai (MDPI journals, 2019-04-08)

To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ...
The Effect of Darapladib Therapy for the Expression of Lp-PLA2 in Dyslipidemia and Type 2 Diabetes Mellitus Atherosclerosis Model

Wihastuti, Titin Andri; Lestari, Rosaria Dian; Heriansyah, Teuku (Journal of Applied Pharmaceutical Science, 2018-04-29)

Atherosclerosis is the main cause of mortality and morbidity globally. Lipoprotein-associated phospholipase A2 (LpPLA2 ) activity is suspected to have a significant role in atherosclerosis. 50 Sprague-Dawley Rats were ...
Comparison of DNA Extraction Methods Between Conventional, Kit, Alkali and Buffer-Only for PCR Amplification on Raw and Boiled Bovine and Porcine Meat

Yahya, Arif; Firmansyah, Marindra; Arlisyah, Annisa; Risandiansyah, Rio (Universitas Brawijaya, 2017)

Detection of porcine contamination in food material by employing PCR techniques is integral in halal food confirmation. However, PCR is both costly and laborious, particularly in DNA isolation method. This study explores ...
Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

Sulistyowati, Erna; Lee, Mei-Yueh; Wu, Lin-Chi; Hsu, Jong-Hau; Dai, Zen-Kong; Wu, Bin-Nan; Lin, Ming-Chung; Yeh, Jwu-Lai (MDPI journals, 2018-08-23)

Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic ...
Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene

Lin, Shao-Lin; Yeh, Jwu-Lai; Chang, Tsung-Hsien; Huang, Wei-Chun; Lee, Song-Tay; Wassler, Michael; Geng, Yong-Jian; Sulistyowati, Erna (Springer, 2018-09-06)

Extracellular superoxide dismutase (EC-SOD) has been implicated in regulation of vascular function but its underlying molecular mechanism is largely unknown. These two-step experiments investigate whether hemagglutinating ...
Lp-PLA2 Selective Inhibitor (Darapladib) Effect In Lowering The Expression Level Of IL-1B And IL-6 In The Renal At Type 2 Diabetes Mellitus

Wihastuti, Titin Andri; Aini, Fitria Nugraha; Tjahjono, Cholid Tri; Sulfia, Yuni Hendrati; Sholichah, Zuhrotus; Heriansyah, Teuku (US National Library of Medicine National Institutes of Health, 2019-11-01)

Purpose The aim of this study is to prove that type 2 diabetes mellitus can induce increasing inflammation marker in renal and that the provision of darapladib as Lp-LA2 Inhibitor agents can inhibit inflammation that were ...
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine

Liou, Shu-Fen; Nguyen, Thi Tuyet Ngan; Hsu, Jong-Hau; Sulistyowati, Erna; Huang, Shang-En; Wu, Bin-Nan; Lin, Ming-Chung; Yeh, Jwu-Lai (MDPI journals, 2020-10-06)

Vascular calcification (VC) is highly prevalent in patients with atherosclerosis, chronic kidney disease, diabetes mellitus, and hypertension. In blood vessels, VC is associated with major adverse cardiovascular events. ...
Evaluasi Hasil Penerapan Model Sms Gateway dalam Promosi Kesehatan Tentang Bahaya Komplikasi Selama Kehamilan

Herlina, Sri (Universitas Almaata & Universitas Islam Indonesia, 2018)

Penerapan teknologi berbasis sms gateway penting dikembangkan sebagai alternatif strategi pendekatan pada komunitas yang sulit terjangkau fasilitas kesehatan dalam rangka menurunkan angka kematian baik pra maternal maupun ...

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