LP - Faculty of Medicine: Recent submissions
Now showing items 41-60 of 61
-
Revealing The Potency of Annona Muricata Leaves Extract as FOXO1 Inhibitor for Diabetes Mellitus Treatment Through Computational Study
(Springer, 2017-06-26)FOXO1 protein inactivation in the nucleus is one of targets for the treatment of diabetes mellitus. Annona muricata leaves contain flavonoid and phenolic compound alkaloids that were known to be able to increase pancreatic ... -
Anti-Inflammatory Activity of Agaricus Blazei Murill Extract In The Spleen of Mice Fed a High-Fat Diet
(Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria, 2018-03-31)urpose: To examine the effects of A. blazei Murill on the production of proinflammatory cytokine TNF-α and regulatory cytokine IL-10 in the spleen of mice fed a high-fat diet. Methods: The study was conducted on 25 BALB/c ... -
In Silico Study to Assess Antibacterial Activity from Cladophora Sp. on Peptide Deformylase: Molecular Docking Approach
(Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya, 2019-05-04)Increasing antibiotic-resistant pathogenic bacteria is a severe problem in the world. Therefore, there is a need to identify new drugs from natural products and also new drug targets. Cladophora sp. is a marine organism ... -
Dietary Ethanolic Extract of Mangosteen pericarp Reduces VCAM-1, Perivascular Adipose Tissue and Aortic Intimal Medial Thickness in Hypercholesterolemic Rat Model
(US National Library of Medicine National Institutes of Health, 2019-10-10)BACKGROUND: High-fat diet (HFD) is associated with dyslipidemia which is a risk factor for atherosclerosis. Dyslipidemia causes oxidative stress which induces vascular cell adhesion molecule-1 (VCAM-1). Oxidative stress ... -
Effects of Soursop (Annona muricata ) Leaf Water Extract (SLWE) on Body Weight, Leptin and TNF α Plasma Levels of Rats with High Fat and High Fructose (HFHF) Diet.
(Journal of Global Pharma Technology, 2019-04)Background: Soursop leaves believed to be able to lose weight. The aim of the study was to prove that SLWE had an effect on body weight, leptin and TNF α plasma level in mice with the HFHF diet . Methods:The study used ... -
Red Yeast Rice Protects Hepatocytes Conditions of Rats Receiving High Fat Diet
(Jurnal Universitas Brawijaya, 2019-03-20)Triglyceride (TG) is a simple and the main lipid of the daily diet. Nowadays, TG is emerging as an independent risk factor for cardiovascular disease, and increasing clinical data that indicate a high level of this simple ... -
The Significance of Agaricus Blazei as an Immunomodulator of The Level of IL-17 in Balb/C mice with Atherosclerosis
(National Center for Biotechnology Information, U.S. National Library of Medicine, 2020-04-20)Atherosclerosis is a disease caused by an inflammatory response which involved the interaction between endothelial cells, macrophages and lymphocytes, and is closely related to IL-17 regulation. This study is important to ... -
Atheroprotective Effect of The Agaricus Blazei Mur ill Extract in High Fat Diet-Induced Mice
(Medicinal Plants, 2017-02-20)The purpose of the present study was to provide evidence of the potential of Agaricus blazei Murill extract as atheroprotective agent. The study was conducted with 25 male mice (Mus musculus) divided into f ive groups ... -
Terapi dengan Dinydroartemisinin Piperaquine (DHP) dapat Mencegah Terjadinya Anemia Tetapi Tidak Dapat Mencegah IUGR pada Mencit Bunting yang di Infeksi Plasmodium berghei
(Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018-03-20)Infeksi malaria dengan Plasmodium falciparum selama kehamilan berhubungan dengan infeksi pada plasenta dan dampak buruk yang luas pada ibu maupun janin yang dikandungnya meliputi salah satunya anemia pada ibu hamil ... -
Indonesian Pasuruan Propolis Extract Does Not Exert Antiproliferation and Pro-Apoptotic Effect on Human Colon Carcinoma Cell Line HT-29
(AFRICAN JOURNALS ONLINE (AJOL), 2018-07-20)Purpose: To evaluate the anti-cancer activity of Indonesian Pasuruan propolis extract (PPE) against HT-29 human colon carcinoma cell line. Methods: HT-29 cells were cultured and treated in different concentrations of PPE ... -
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER SHEET (SHEET MASK) KOMBINASI VCO (VIRGIN COCONUT OIL), ASAM ASKORBAT DAN α-TOCOPHEROL
(Fakultas Farmasi, Universitas Buana Perjuangan Karawang, 2020-05-09)Kulit yang sehat dapat mencerminkan kesehatan seseorang. Menjadikan kulit sehat, bersih dan cerah merupakan idaman semua orang terutama pada wanita. Antioksidan melindungi tubuh dari kerusakan yang disebabkan oleh radikal ... -
Effect of ascorbic acid, α-tocopherol and its combination on human umbilical vein endothelial cells permeability exposed to high concentration of glucose
(Russian Open Medical Journal, 2019-05-28)Aim — To evaluate the effect of ascorbic acid, α-tocopherol, and its combination on the permeability of human umbilical vein endothelial cells (HUVEC’S) culture after high glucose concentration exposure. Material and ... -
Acute Toxicity Level of Pulutan (Urena lobata) Leaf Extract on Zebrafish (Danio rerio) and its Analysis by In Silico Study
(The Japanese Pharmacological Society, The Japanese Society of Clinical Pharmacology, 2018-07-06)Pulutan (Urena lobata) is medicinal plant used to treat some diseases empirically, with pre-clinical study has already proven its efficacy, however, its safety has not been evaluated. Acute toxicity has to be performed on ... -
Inhibitory activity of Urena lobata leaf extract on dipeptidyl peptidase-4 (DPP-4):
(Society For Conservation And Resource Development Of Medicinal Plants, 2018-05-25)This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ... -
Antidiabetic Effect of Urena lobata: Preliminary Study on Hexane, Ethanolic, and Aqueous Leaf Extracts
(Jurnal Universitas Brawijaya, 2018-02-20)Chronic hyperglycemia is one of the signs of human type-2 diabetes mellitus due to insulin resistance and depletion. This study aimed to evaluate hexane, ethanolic, and aqueous leaf extracts of Urena lobata as antihyperglycemic ... -
Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells
(Elsevier, 2017-07-20)This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test ... -
The difference of map1lc3 level as macrophage autophagy Marker between resistant and sensitive tuberculosis patients on rifampicin
(Lembaga Penyakit Tropis (Institute of Tropical Disease) Universitas Airlangga, 2018-04-01)M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be ... -
The Influence of Ratio Pyridine and Triethylamine Catalysts on Synthesis 2-Phenyl-Benzo[D] [1,3] Oxazine-4-On Derivatives
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)The aim of this research was to compare the effect of pyridine and triethylamine catalyst ratios on the synthesis of 2-phenyl-benzo(d)[1,3] oxazine-4-one derivatives. The catalysts used were triethylene amine (100%), ... -
Synthesis, Method Optimization of 2,3-Disubtitutedquinazolin-4(3H)-One
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)Quinzolinones have various biological activities such as anticancer, antidiabetic, anticonvulsant, antihistaminic, anti inflammatory, antifungal, anthelmintics and antiviral activites. In this research some of compounds ... -
Design and Molecular Docking Studies of Quinazoline Derivatives as Antiproliferation
(Fakultas Farmasi Universitas Airlangga, 2016-12-02)Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ...