Browsing LP - Medical Education by Title
Now showing items 1-20 of 34
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Anti-Inflammatory Activity of Agaricus Blazei Murill Extract In The Spleen of Mice Fed a High-Fat Diet
(Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria, 2018-03-31)urpose: To examine the effects of A. blazei Murill on the production of proinflammatory cytokine TNF-α and regulatory cytokine IL-10 in the spleen of mice fed a high-fat diet. Methods: The study was conducted on 25 BALB/c ... -
Association of LL-37 and IL-31 Serum Levels with SCORing Atopic Dermatitis (SCORAD) Score in Atopic Dermatitis Patients
(Iranian Journal of Dermatology, 2018-05-12)Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic ... -
Atheroprotective Effect of The Agaricus Blazei Mur ill Extract in High Fat Diet-Induced Mice
(Medicinal Plants, 2017-02-20)The purpose of the present study was to provide evidence of the potential of Agaricus blazei Murill extract as atheroprotective agent. The study was conducted with 25 male mice (Mus musculus) divided into f ive groups ... -
Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation
(Elsevier, 2018)Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ... -
Combined Effects of Shear Stress and Glucose on the Morphology, Actin Filaments, and VE-Cadherin of Endothelial Cells in Vitro
(Elsevier, 2017-06-07)Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin. Methods: After ... -
Comparison of DNA Extraction Methods Between Conventional, Kit, Alkali and Buffer-Only for PCR Amplification on Raw and Boiled Bovine and Porcine Meat
(Universitas Brawijaya, 2017)Detection of porcine contamination in food material by employing PCR techniques is integral in halal food confirmation. However, PCR is both costly and laborious, particularly in DNA isolation method. This study explores ... -
Dietary Ethanolic Extract of Mangosteen pericarp Reduces VCAM-1, Perivascular Adipose Tissue and Aortic Intimal Medial Thickness in Hypercholesterolemic Rat Model
(US National Library of Medicine National Institutes of Health, 2019-10-10)BACKGROUND: High-fat diet (HFD) is associated with dyslipidemia which is a risk factor for atherosclerosis. Dyslipidemia causes oxidative stress which induces vascular cell adhesion molecule-1 (VCAM-1). Oxidative stress ... -
The Effect of Darapladib Therapy for the Expression of Lp-PLA2 in Dyslipidemia and Type 2 Diabetes Mellitus Atherosclerosis Model
(Journal of Applied Pharmaceutical Science, 2018-04-29)Atherosclerosis is the main cause of mortality and morbidity globally. Lipoprotein-associated phospholipase A2 (LpPLA2 ) activity is suspected to have a significant role in atherosclerosis. 50 Sprague-Dawley Rats were ... -
Effects of Soursop (Annona muricata ) Leaf Water Extract (SLWE) on Body Weight, Leptin and TNF α Plasma Levels of Rats with High Fat and High Fructose (HFHF) Diet.
(Journal of Global Pharma Technology, 2019-04)Background: Soursop leaves believed to be able to lose weight. The aim of the study was to prove that SLWE had an effect on body weight, leptin and TNF α plasma level in mice with the HFHF diet . Methods:The study used ... -
Evaluasi Hasil Penerapan Model Sms Gateway dalam Promosi Kesehatan Tentang Bahaya Komplikasi Selama Kehamilan
(Universitas Almaata & Universitas Islam Indonesia, 2018)Penerapan teknologi berbasis sms gateway penting dikembangkan sebagai alternatif strategi pendekatan pada komunitas yang sulit terjangkau fasilitas kesehatan dalam rangka menurunkan angka kematian baik pra maternal maupun ... -
Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages
(MDPI journals, 2018-08-23)Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic ... -
HUBUNGAN KUANTITATIF STRUKTUR-PROPERTI (HKSP) SENYAWA AKTIF TEMU KUNCI (BOESENBERGIA PANDURATA) SEBAGAI PENGHAMBAT ENZIM MAIN PROTEASE (MPRO) SARS-CoV-2
(Sanata Dharma University Press, 2022-12-10)Hubungan parameter fisikokimia dari 15 senyawa aktif Boesenbergia pandurata dalam menghambat enzim main protease SARS-CoV-2 diprediksi melalui model Hubungan Kuantitatif Struktur-Properti (HKSP). Semua senyawa aktif ... -
In Silico Study to Assess Antibacterial Activity from Cladophora Sp. on Peptide Deformylase: Molecular Docking Approach
(Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya, 2019-05-04)Increasing antibiotic-resistant pathogenic bacteria is a severe problem in the world. Therefore, there is a need to identify new drugs from natural products and also new drug targets. Cladophora sp. is a marine organism ... -
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
(National Library of Medicine, 2021-05-28)Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ... -
Indonesian Herbal Medicine Prevents Hypertension-Induced Left Ventricular Hypertrophy by Diminishing NADPH Oxidase-Dependent Oxidative Stress
(US National Library of Medicine National Institutes of Health, 2017-09-30)Indonesian herbal medicine Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension. Oxidative stress plays an important role in hypertension-induced ... -
Indonesian Pasuruan Propolis Extract Does Not Exert Antiproliferation and Pro-Apoptotic Effect on Human Colon Carcinoma Cell Line HT-29
(AFRICAN JOURNALS ONLINE (AJOL), 2018-07-20)Purpose: To evaluate the anti-cancer activity of Indonesian Pasuruan propolis extract (PPE) against HT-29 human colon carcinoma cell line. Methods: HT-29 cells were cultured and treated in different concentrations of PPE ... -
Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene
(Springer, 2018-09-06)Extracellular superoxide dismutase (EC-SOD) has been implicated in regulation of vascular function but its underlying molecular mechanism is largely unknown. These two-step experiments investigate whether hemagglutinating ... -
The Interaction of β-Glucan on Dectin-1 Receptor or TLR-2 Might Have the Potency to Activate Function of Treg Cell and Production of Anti-Inflammatory Cytokine
(EurAsian Journal of BioSciences, 2020-03-20)Objectives: Atherosclerosis formed due to the accumulation of the fibrous tissues in the vascular wall and gradually become thrombus. Agaricus brasiliensis known as a traditional drug for lifestylerelated diseases, including ... -
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways
(MDPI journals, 2019-04-08)To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ...