LP - Medical Education: Recent submissions
Now showing items 1-20 of 34
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HUBUNGAN KUANTITATIF STRUKTUR-PROPERTI (HKSP) SENYAWA AKTIF TEMU KUNCI (BOESENBERGIA PANDURATA) SEBAGAI PENGHAMBAT ENZIM MAIN PROTEASE (MPRO) SARS-CoV-2
(Sanata Dharma University Press, 2022-12-10)Hubungan parameter fisikokimia dari 15 senyawa aktif Boesenbergia pandurata dalam menghambat enzim main protease SARS-CoV-2 diprediksi melalui model Hubungan Kuantitatif Struktur-Properti (HKSP). Semua senyawa aktif ... -
Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation
(Elsevier, 2018)Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ... -
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
(National Library of Medicine, 2021-05-28)Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ... -
Vasculoprotective Effects of Centella Asiatica, Justicia Gendarussa and Imperata Cylindrica Decoction via the NOXs-ROS-NF-κB Pathway in Spontaneously Hypertensive Rats
(Elsevier, 2019-06-24)Background and aim: Centella asiatica,Justicia gendarussaandImperata cylindricadecoction (CJID) isefficacious for hypertension. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-induced reactive oxygen ... -
Association of LL-37 and IL-31 Serum Levels with SCORing Atopic Dermatitis (SCORAD) Score in Atopic Dermatitis Patients
(Iranian Journal of Dermatology, 2018-05-12)Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic ... -
Combined Effects of Shear Stress and Glucose on the Morphology, Actin Filaments, and VE-Cadherin of Endothelial Cells in Vitro
(Elsevier, 2017-06-07)Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin. Methods: After ... -
Indonesian Herbal Medicine Prevents Hypertension-Induced Left Ventricular Hypertrophy by Diminishing NADPH Oxidase-Dependent Oxidative Stress
(US National Library of Medicine National Institutes of Health, 2017-09-30)Indonesian herbal medicine Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension. Oxidative stress plays an important role in hypertension-induced ... -
The Interaction of β-Glucan on Dectin-1 Receptor or TLR-2 Might Have the Potency to Activate Function of Treg Cell and Production of Anti-Inflammatory Cytokine
(EurAsian Journal of BioSciences, 2020-03-20)Objectives: Atherosclerosis formed due to the accumulation of the fibrous tissues in the vascular wall and gradually become thrombus. Agaricus brasiliensis known as a traditional drug for lifestylerelated diseases, including ... -
The Prophylactic Effects of Pomegranate Peel in a Rat Model of Rheumatoid Arthritis: Study on Arthritis Score and Expression of Inflammatory Markers
(Jurnal Universitas Brawijaya, 2020)Rheumatoid arthritis (RA) is a joint disease, chronically cause permanent joint impairment leading to inability of daily life activities. Early diagnosis and preven tive managements of RA are recommended to overcome the ... -
The Potency of Soursop Leaf Water Extract on Activating GLP-1R, Inhibiting DPP4 And FoxO1 Protein Based on in Silico Analysis
(International Journal of Applied Pharmaceutics, 2019-12-15)Objective: Soursop leaf contains alkaloids, terpenoids, flavonoids, acetogenin, and phenolics. Soursop leaf decoction is usually consumed as an anti obesity agent, even though its active compounds and its action mechanism ... -
Study of Superoxide Dismutase and Malondialdehyde Concentrations in Mice After Administration of Methanolic Extract of Scurrula Atropurpurea (BL.)
(Fakultas Kedokteran Hewan, Universitas Syiah Kuala, 2017-03)The aim of this research was to investigate the potential effect of methanolic extract of Scurrula atropurpurea (MESA) in reducing oxidative stress through observation of superoxide dismutase (SOD) activity and malondialdehyde ... -
Perbedaan Ekspresi Protein Cyclin D1 antara Adenoma dan Adenokarsinoma Kolorektal, serta Korelasinya dengan Grading dan Stadium Tumor
(Fakultas Kedokteran Universitas Brawijaya, 2020-03-20)Sebagian besar karsinoma kolorektal adalah adenokarsinoma, dan lebih dari 95% karsinoma kolorektal diawali oleh lesi prekursor yaitu adenoma. Risiko suatu adenoma berubah menjadi suatu karsinoma akan lebih tinggi pada ... -
Korelasi IgE Terhadap Rasio Neutrofil/Eosinofil Jaringan dan Darah Penderita Rinosinusitis Kronik Aspergillus Fumigatus
(Oto Rhino Laryngologica Indonesiana, 2018-06-01)Latar Belakang: Prevalensi rinosinusitis kronik (RSK) jamur saat ini cenderung meningkat. Jamur berperan sebagai mikroorganisme dan merupakan salah satu penyebab RSK. Pemeriksaan immunoglobulin E (IgE) Aspergillus ... -
Profile of Patients with Floaters in Saiful Anwar Hospital Malang
(Indonesian Vitreoretinal Society, 2018-08-24)Introduction: To report the profile of patients with floaters as a subjective complain in Saiful Anwar Hospital from July 2012 until June 2013. Methods: an observasional descriptive study was conducted, collecting data ... -
Metode Slow Sand Filter dan Pengukuran MPN Coliform Sebagai Upaya Peningkatan Kualitas Air Sungai di Pekapuran Raya Banjarmasin
(Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018)Sungai Pekapuran Raya Banjarmasin merupakan salah satu kawasan pinggiran sungai yang padat penduduk, saat musim kemarau kondisi sungai terlihat dangkal dipenuhi tumpukan sampah, berwarna kecoklatan dan keruh. Penelitian ... -
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways
(MDPI journals, 2019-04-08)To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ... -
The Effect of Darapladib Therapy for the Expression of Lp-PLA2 in Dyslipidemia and Type 2 Diabetes Mellitus Atherosclerosis Model
(Journal of Applied Pharmaceutical Science, 2018-04-29)Atherosclerosis is the main cause of mortality and morbidity globally. Lipoprotein-associated phospholipase A2 (LpPLA2 ) activity is suspected to have a significant role in atherosclerosis. 50 Sprague-Dawley Rats were ... -
Comparison of DNA Extraction Methods Between Conventional, Kit, Alkali and Buffer-Only for PCR Amplification on Raw and Boiled Bovine and Porcine Meat
(Universitas Brawijaya, 2017)Detection of porcine contamination in food material by employing PCR techniques is integral in halal food confirmation. However, PCR is both costly and laborious, particularly in DNA isolation method. This study explores ... -
Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages
(MDPI journals, 2018-08-23)Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic ...