LP - Medical Education: Recent submissions

Now showing items 1-20 of 34

HUBUNGAN KUANTITATIF STRUKTUR-PROPERTI (HKSP) SENYAWA AKTIF TEMU KUNCI (BOESENBERGIA PANDURATA) SEBAGAI PENGHAMBAT ENZIM MAIN PROTEASE (MPRO) SARS-CoV-2

Widiyana, Anita Puspa (Sanata Dharma University Press, 2022-12-10)

Hubungan parameter fisikokimia dari 15 senyawa aktif Boesenbergia pandurata dalam menghambat enzim main protease SARS-CoV-2 diprediksi melalui model Hubungan Kuantitatif Struktur-Properti (HKSP). Semua senyawa aktif ...
Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation

Yang, Dongqing; Anderson, Paul H.; Wijeyanaka, Asiri R.; Barratt, Kate R.; Triliana, Rahma; Stapledon, Catherine J.M.; Zhou, Hong; Findlay, David M.; Morris, Howard A.; Atkins, Gerald J. (Elsevier, 2018)

Previous studies have shown that 1α,25-dihydroxyvitamin D3 (1,25D) through vitamin D receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. However, the mechanism of these differential ...
Cardiovascular protective effect of Indonesian herbal medicine in spontaneously hypertensive rats

Yeh, Jwu-Lai; Sulistyowati, Erna (J-STAGE, 2018)
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis

Huang, Shang-En; Sulistyowati, Erna; Chao, Yu-Ying; Wu, Bin-Nan; Dai, Zen-Kong; Hsu, Jong-Hau; Yeh, Jwu-Lai (National Library of Medicine, 2021-05-28)

Osteoarthritis is a degenerative arthropathy that is mainly characterized by dysregulation of inflammatory responses. KMUP-1, a derived chemical synthetic of xanthine, has been shown to have anti-inflammatory and antioxidant ...
Vasculoprotective Effects of Centella Asiatica, Justicia Gendarussa and Imperata Cylindrica Decoction via the NOXs-ROS-NF-κB Pathway in Spontaneously Hypertensive Rats

Sulistyowati, Erna; Jan, Ren-Long; Liou, Shu-Fen; Chen, Ying-Fu; Wu, Bin-Nan; Hsu, Jong-Hau; Yeh, Jwu-Lai (Elsevier, 2019-06-24)

Background and aim: Centella asiatica,Justicia gendarussaandImperata cylindricadecoction (CJID) isefficacious for hypertension. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-induced reactive oxygen ...
Association of LL-37 and IL-31 Serum Levels with SCORing Atopic Dermatitis (SCORAD) Score in Atopic Dermatitis Patients

Brahmanti, Herwinda; Rofiq, Aunur; Cholis, Moch; Trijayanti, Unundya; Purwanti, Sasi (Iranian Journal of Dermatology, 2018-05-12)

Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic ...
Combined Effects of Shear Stress and Glucose on the Morphology, Actin Filaments, and VE-Cadherin of Endothelial Cells in Vitro

Sulistyowati, Erna; Permatasari, Nur; Widodo, M Aris (Elsevier, 2017-06-07)

Objective: The purpose of the present study was to analyze the effects of glucose and shear stress on the morphol ogy and density of endothelial cells, actin filamen, and the expression of VE-cadherin. Methods: After ...
Indonesian Herbal Medicine Prevents Hypertension-Induced Left Ventricular Hypertrophy by Diminishing NADPH Oxidase-Dependent Oxidative Stress

Sulistyowati, Erna; Hsu, Jong-Hau; Cheng, Yuan-Bin; Chang, Fang-Rong; Cheng, Ying-Fu; Yeh, Jwu-Lai (US National Library of Medicine National Institutes of Health, 2017-09-30)

Indonesian herbal medicine Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction (CJID) are known to be efficacious for hypertension. Oxidative stress plays an important role in hypertension-induced ...
The Interaction of β-Glucan on Dectin-1 Receptor or TLR-2 Might Have the Potency to Activate Function of Treg Cell and Production of Anti-Inflammatory Cytokine

Kurniawan, Dicky; Sargowo, Djanggan; Tjokroprawiro, Askandar; Rifa'i, Muhaimin (EurAsian Journal of BioSciences, 2020-03-20)

Objectives: Atherosclerosis formed due to the accumulation of the fibrous tissues in the vascular wall and gradually become thrombus. Agaricus brasiliensis known as a traditional drug for lifestylerelated diseases, including ...
The Prophylactic Effects of Pomegranate Peel in a Rat Model of Rheumatoid Arthritis: Study on Arthritis Score and Expression of Inflammatory Markers

Wahyuningsih, Doti; Amalia, Annisa; Amiruddin, Meilano Setiawan; Cahyaningrum, Asri; Kurniasari, Laili Chintianur (Jurnal Universitas Brawijaya, 2020)

Rheumatoid arthritis (RA) is a joint disease, chronically cause permanent joint impairment leading to inability of daily life activities. Early diagnosis and preven tive managements of RA are recommended to overcome the ...
The Potency of Soursop Leaf Water Extract on Activating GLP-1R, Inhibiting DPP4 And FoxO1 Protein Based on in Silico Analysis

Damayanti, Dini Sri; Nurdiana; Kusuma, Chandra; Soeadmadji, Djoko Wahono (International Journal of Applied Pharmaceutics, 2019-12-15)

Objective: Soursop leaf contains alkaloids, terpenoids, flavonoids, acetogenin, and phenolics. Soursop leaf decoction is usually consumed as an anti obesity agent, even though its active compounds and its action mechanism ...
Study of Superoxide Dismutase and Malondialdehyde Concentrations in Mice After Administration of Methanolic Extract of Scurrula Atropurpurea (BL.)

Athiro, Nour; Wahyuningsih, Doti (Fakultas Kedokteran Hewan, Universitas Syiah Kuala, 2017-03)

The aim of this research was to investigate the potential effect of methanolic extract of Scurrula atropurpurea (MESA) in reducing oxidative stress through observation of superoxide dismutase (SOD) activity and malondialdehyde ...
Perbedaan Ekspresi Protein Cyclin D1 antara Adenoma dan Adenokarsinoma Kolorektal, serta Korelasinya dengan Grading dan Stadium Tumor

Rosidah, Aris; Norahmawati, Eviana; Anita, Kenty Wanty; Rasyid, Harun Al (Fakultas Kedokteran Universitas Brawijaya, 2020-03-20)

Sebagian besar karsinoma kolorektal adalah adenokarsinoma, dan lebih dari 95% karsinoma kolorektal diawali oleh lesi prekursor yaitu adenoma. Risiko suatu adenoma berubah menjadi suatu karsinoma akan lebih tinggi pada ...
Korelasi IgE Terhadap Rasio Neutrofil/Eosinofil Jaringan dan Darah Penderita Rinosinusitis Kronik Aspergillus Fumigatus

Duhitatrissari, Fifin Pradina; Retnoningsih, Endang; Maharani, Iriana (Oto Rhino Laryngologica Indonesiana, 2018-06-01)

Latar Belakang: Prevalensi rinosinusitis kronik (RSK) jamur saat ini cenderung meningkat. Jamur berperan sebagai mikroorganisme dan merupakan salah satu penyebab RSK. Pemeriksaan immunoglobulin E (IgE) Aspergillus ...
Profile of Patients with Floaters in Saiful Anwar Hospital Malang

Hidayah, Fenti Kusumawardhani; Dewi, Nadia Artha; Refa, Safaruddin (Indonesian Vitreoretinal Society, 2018-08-24)

Introduction: To report the profile of patients with floaters as a subjective complain in Saiful Anwar Hospital from July 2012 until June 2013. Methods: an observasional descriptive study was conducted, collecting data ...
Metode Slow Sand Filter dan Pengukuran MPN Coliform Sebagai Upaya Peningkatan Kualitas Air Sungai di Pekapuran Raya Banjarmasin

Herlina, Sri (Faculty of Medical and Health Sciences, Universitas Islam Negeri Maulana Malik Ibrahim, 2018)

Sungai Pekapuran Raya Banjarmasin merupakan salah satu kawasan pinggiran sungai yang padat penduduk, saat musim kemarau kondisi sungai terlihat dangkal dipenuhi tumpukan sampah, berwarna kecoklatan dan keruh. Penelitian ...
KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

Lee, Meng-Luen; Sulistyowati, Erna; Hsu, Jong-Hau; Huang, Bo-Yau; Dai, Zen-Kong; Wu, Bin-Nan; Chao, Yu-Ying; Yeh, Jwu-Lai (MDPI journals, 2019-04-08)

To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the ...
The Effect of Darapladib Therapy for the Expression of Lp-PLA2 in Dyslipidemia and Type 2 Diabetes Mellitus Atherosclerosis Model

Wihastuti, Titin Andri; Lestari, Rosaria Dian; Heriansyah, Teuku (Journal of Applied Pharmaceutical Science, 2018-04-29)

Atherosclerosis is the main cause of mortality and morbidity globally. Lipoprotein-associated phospholipase A2 (LpPLA2 ) activity is suspected to have a significant role in atherosclerosis. 50 Sprague-Dawley Rats were ...
Comparison of DNA Extraction Methods Between Conventional, Kit, Alkali and Buffer-Only for PCR Amplification on Raw and Boiled Bovine and Porcine Meat

Yahya, Arif; Firmansyah, Marindra; Arlisyah, Annisa; Risandiansyah, Rio (Universitas Brawijaya, 2017)

Detection of porcine contamination in food material by employing PCR techniques is integral in halal food confirmation. However, PCR is both costly and laborious, particularly in DNA isolation method. This study explores ...
Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

Sulistyowati, Erna; Lee, Mei-Yueh; Wu, Lin-Chi; Hsu, Jong-Hau; Dai, Zen-Kong; Wu, Bin-Nan; Lin, Ming-Chung; Yeh, Jwu-Lai (MDPI journals, 2018-08-23)

Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic ...

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