Browsing LP - Pharmaceutical by Title
Now showing items 8-27 of 27
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Design and Molecular Docking Studies of Quinazoline Derivatives as Antiproliferation
(Fakultas Farmasi Universitas Airlangga, 2016-12-02)Background: Nowadays, a lot of new active substances as anticancer agents have been developed. One of the protein targets of anticancer is selective cyclooxygenase-2 (COX-2). Selective COX-2 is the regulator of cell ... -
The difference of map1lc3 level as macrophage autophagy Marker between resistant and sensitive tuberculosis patients on rifampicin
(Lembaga Penyakit Tropis (Institute of Tropical Disease) Universitas Airlangga, 2018-04-01)M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP KADAR SOD DAN MDA PADA AORTA TIKUS MODEL DIABETES MELITUS TIPE 2
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-03-01)Hiperglikemia pada diabetes melitus (DM) meningkatkan produksi reactive oxygen species (ROS) yang berperan terhadap komplikasi makroangiopati diabetik. Daun gedi merah dikenal memiliki efek antioksidan dan antihiperglikemia ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (ABELMOSCHUS MANIHOT (L.) MEDIK) TERHADAP KADAR SUPEROXIDE DISMUTASE DAN MALONDIALDEHYDE JARINGAN GINJAL TIKUS MODEL DIABETES MELITUS TIPE 2
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2020-09-12)Hiperglikemia pada Diabetes Melitus (DM) meningkatkan produksi Reactive Oxygen Species (ROS) dan berperan terhadap risiko komplikasi nefropati diabetik. Daun gedi merah (Abelmoschus manihot (L.) Medik) berkhasiat sebagai ... -
EFEK EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus manihot (L.) Medik) TERHADAP PERSENTASE INTERLEUKIN-10 (IL-10) DAN SEL T SITOTOKSIK (CD8+ ) TIKUS MODEL DIABETES Tipe II
(Jurnal Kesehatan Islam - Fakultas Kedokteran, Universitas Islam Malang, 2019-03-01)Inflamasi akibat kerusakan oksidatif yang dipicu hiperglikemia berperan terhadap progresivitas diabetes melitus (DM). Interleukin-10 (IL-10) dan CD8+ berpengaruh terhadap proses inflamasi. Abelmoschus manihot (L.) Medik ... -
EFEK KOMBINASI SEFTRIAKSON DAN KLORAMFENIKOL PADA Staphylococcus aureus DARI ISOLAT GANGREN DIABETIK
(Jurnal Farmasi Galenika, 2022-03-01)Diabetic gangrene is a complication of Diabetes mellitus caused by Staphylococcus aureus. The combination of Ceftriaxone and Chloramphenicol is often used to cure gangrene infection, even though, they produce antagonist ... -
Effect of ascorbic acid, α-tocopherol and its combination on human umbilical vein endothelial cells permeability exposed to high concentration of glucose
(Russian Open Medical Journal, 2019-05-28)Aim — To evaluate the effect of ascorbic acid, α-tocopherol, and its combination on the permeability of human umbilical vein endothelial cells (HUVEC’S) culture after high glucose concentration exposure. Material and ... -
Effect of Extraction Method on Antimicrobial Activity Against Staphylococcus Aureus of Tapak Liman (Elephantopus Scaber L.) Leaves
(International journal of Health & Medical Sciences, 2020-10-18)This study aims to compare the antibacterial activity of Staphylococcus aureus from tapak liman leaf extract using different extraction methods, maceration, and soxhletation. Maceration is a type of cold extraction, ... -
Effect of Pulutan (Urena lobata) Leaf Extract on Blood Glucose Level, Hemoglobin and Body Growth of Zebra Fish (Danio rerio) Exposed to Malathion
(Tropical Journal of Natural Product Research (TJNPR), 2021-06-01)Pulutan (Urena lobata) is a medicinal plant having antioxidant activity. However, their potency to inhibit the adverse effects of malathion has not been evaluated. The study aims to examine Urena lobata (U. lobata) leaves ... -
Factors related to rational antibiotic prescriptions in community health centers in Depok City, Indonesia
(Elsevier, 2016-01-12)Irrational antibiotic prescription is common in developing countries, including in Indonesia. The aims of this study were to evaluate antibiotic prescription patterns and the factors related to the rationale for antibiotic ... -
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER SHEET (SHEET MASK) KOMBINASI VCO (VIRGIN COCONUT OIL), ASAM ASKORBAT DAN α-TOCOPHEROL
(Fakultas Farmasi, Universitas Buana Perjuangan Karawang, 2020-05-09)Kulit yang sehat dapat mencerminkan kesehatan seseorang. Menjadikan kulit sehat, bersih dan cerah merupakan idaman semua orang terutama pada wanita. Antioksidan melindungi tubuh dari kerusakan yang disebabkan oleh radikal ... -
In Silico Study of Pulutan (Urena lobata) Leaf Extract as Anti Inflammation and their ADME Prediction
(Journal of Tropical Pharmacy and Chemistry (JTPC), 2022-06-30)Inflammation is the basic for the pathogenesis of several diseases both of degenerative and non-degenerative disease. Urena lobata is a medicinal plant that can be found in Indonesia and has been used traditionally to cure ... -
Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells
(Elsevier, 2017-07-20)This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test ... -
The Influence of Ratio Pyridine and Triethylamine Catalysts on Synthesis 2-Phenyl-Benzo[D] [1,3] Oxazine-4-On Derivatives
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)The aim of this research was to compare the effect of pyridine and triethylamine catalyst ratios on the synthesis of 2-phenyl-benzo(d)[1,3] oxazine-4-one derivatives. The catalysts used were triethylene amine (100%), ... -
Inhibitory activity of Urena lobata leaf extract on alpha-amylase and alpha-glucosidase: in vitro and in silico approach
(Journal of Basic and Clinical Physiology and Pharmacology, 2021-11-21)In food ingestion, alpha-glucosidase (α-glucosidase) and alpha-amylase (α-amylase) are enzymes that are responsible to convert a carbohydrate into glucose. Inhibition of both enzyme activities can prolong absorption of ... -
Inhibitory activity of Urena lobata leaf extract on dipeptidyl peptidase-4 (DPP-4):
(Society For Conservation And Resource Development Of Medicinal Plants, 2018-05-25)This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ... -
Inhibitory activity of Urena lobata leaf extract on dipeptidyl peptidase-4 (DPP-4): Is it different in vitro and in vivo?
(Medicinal Plants - International Journal of Phytomedicines and Related Industries, 2018-05-28)This study was aimed to compare the anti diabetic effect of Urena lobata leaf extract through DPP-4 inhibitory activity by in vitro and in vivo. Urena lobata leaf was extracted in ethanol and hot water to evaluate its ... -
Molecular Docking of Soybean (Glycine max) Seed and Ginger (Zingiber officinale) Rhizome Components as Anti-Diabetic Through Inhibition of Dipeptidyl Peptidase 4 (DPP-4) and Alpha-Glucosidase Enzymes
(Tropical Journal of Natural Product Research, 2021-10-01)Dipeptidyl Peptidase-4 (DPP-4) and alpha-glucosidase (α-glucosidase) are enzymes involved in carbohydrate metabolism. Inhibition of these enzymes contribute to blood glucose level suppression. Soybean (Glycine max) seeds ... -
Potensi Toleransi Oral Glukosa Ekstrak Biji Kedelai (Glycine Max), Rimpang Jahe (Zingiber Officinale) Dan Kombinasinya Pada Tikus Model Diabetes
(Jurnal Kesehatan Islam (JKI), 2018-09-20)Diabetes Mellitus (DM) adalah sindrom metabolik yang ditandai peningkatan kadar glukosa darah kronik dan berkontribusi terhadap beberapa resiko komplikasi. Biji Kedelai(G.max) danrimpang Jahe (Z.officinale) digunakan sebagai ... -
Synthesis, Method Optimization of 2,3-Disubtitutedquinazolin-4(3H)-One
(Journal of Chemical and Pharmaceutical Research (JOCPR), 2017-08-01)Quinzolinones have various biological activities such as anticancer, antidiabetic, anticonvulsant, antihistaminic, anti inflammatory, antifungal, anthelmintics and antiviral activites. In this research some of compounds ...